Citation 105662

FREDENHAGEN,A: METT,H: MEYER,T: BUCHDUNGER,E: REGENASS,U: ROGGO,BE: PETERSEN,F:. (1995). PROTEIN TYROSINE KINASE AND PROTEIN KINASE C INHIBITION BY FUNGAL ANTHRAQUINONES RELATED TO EMODIN.. 48(11)

Citation Details

Title	PROTEIN TYROSINE KINASE AND PROTEIN KINASE C INHIBITION BY FUNGAL ANTHRAQUINONES RELATED TO EMODIN.
Authors	FREDENHAGEN,A: METT,H: MEYER,T: BUCHDUNGER,E: REGENASS,U: ROGGO,BE: PETERSEN,F:
Year	1995
Volume	48
Issue	11

Summary

Year: 1995

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	WEAK ACTIVITY
2	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	ACTIVE
3	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	WEAK ACTIVITY
4	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	WEAK ACTIVITY
5	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	INACTIVE
6	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	WEAK ACTIVITY
7	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	WEAK ACTIVITY
8	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PURPURIN	WEAK ACTIVITY
2	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PURPURIN	WEAK ACTIVITY
3	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PURPURIN	WEAK ACTIVITY
4	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PURPURIN	WEAK ACTIVITY
5	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PURPURIN	WEAK ACTIVITY
6	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PURPURIN	WEAK ACTIVITY
7	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PURPURIN	WEAK ACTIVITY
8	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CATENARIN	WEAK ACTIVITY
9	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CATENARIN	WEAK ACTIVITY
10	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CATENARIN	WEAK ACTIVITY
11	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CATENARIN	WEAK ACTIVITY
12	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CATENARIN	INACTIVE
13	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CATENARIN	INACTIVE
14	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CATENARIN	WEAK ACTIVITY
15	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CATENARIN	WEAK ACTIVITY
16	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIC ACID	WEAK ACTIVITY
17	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIC ACID	WEAK ACTIVITY
18	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIC ACID	WEAK ACTIVITY
19	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIC ACID	WEAK ACTIVITY
20	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIC ACID	INACTIVE
21	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIC ACID	WEAK ACTIVITY
22	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIC ACID	WEAK ACTIVITY
23	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIC ACID	WEAK ACTIVITY
24	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,1-METHYL:	WEAK ACTIVITY
25	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,1-METHYL:	WEAK ACTIVITY
26	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,1-METHYL:	INACTIVE
27	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,1-METHYL:	INACTIVE
28	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,1-METHYL:	INACTIVE
29	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,1-METHYL:	INACTIVE
30	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,1-METHYL:	WEAK ACTIVITY
31	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,1-METHYL:	WEAK ACTIVITY
32	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,8-METHYL:	WEAK ACTIVITY
33	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,8-METHYL:	WEAK ACTIVITY
34	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,8-METHYL:	INACTIVE
35	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,8-METHYL:	INACTIVE
36	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,8-METHYL:	INACTIVE
37	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,8-METHYL:	WEAK ACTIVITY
38	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,8-METHYL:	WEAK ACTIVITY
39	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,8-METHYL:	WEAK ACTIVITY
40	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,2-CHLORO-OMEGA-HYDROXY:	WEAK ACTIVITY
41	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,2-CHLORO-OMEGA-HYDROXY:	WEAK ACTIVITY
42	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,2-CHLORO-OMEGA-HYDROXY:	WEAK ACTIVITY
43	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,2-CHLORO-OMEGA-HYDROXY:	INACTIVE
44	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,2-CHLORO-OMEGA-HYDROXY:	INACTIVE
45	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,2-CHLORO-OMEGA-HYDROXY:	WEAK ACTIVITY
46	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,2-CHLORO-OMEGA-HYDROXY:	WEAK ACTIVITY
47	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN,2-CHLORO-OMEGA-HYDROXY:	WEAK ACTIVITY
48	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ENDOCROCIN	WEAK ACTIVITY
49	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ENDOCROCIN	WEAK ACTIVITY
50	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ENDOCROCIN	WEAK ACTIVITY
51	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ENDOCROCIN	WEAK ACTIVITY
52	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ENDOCROCIN	WEAK ACTIVITY
53	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ENDOCROCIN	INACTIVE
54	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ENDOCROCIN	WEAK ACTIVITY
55	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ENDOCROCIN	WEAK ACTIVITY
56	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE A	WEAK ACTIVITY
57	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE A	ACTIVE
58	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE A	ACTIVE
59	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE A	WEAK ACTIVITY
60	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE A	INACTIVE
61	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE A	INACTIVE
62	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE A	WEAK ACTIVITY
63	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE A	WEAK ACTIVITY
64	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE B	WEAK ACTIVITY
65	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE B	WEAK ACTIVITY
66	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE B	INACTIVE
67	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE B	INACTIVE
68	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE B	INACTIVE
69	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE B	INACTIVE
70	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE B	WEAK ACTIVITY
71	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE B	WEAK ACTIVITY
72	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE C	WEAK ACTIVITY
73	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE C	ACTIVE
74	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE C	WEAK ACTIVITY
75	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE C	WEAK ACTIVITY
76	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE C	INACTIVE
77	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE C	WEAK ACTIVITY
78	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE C	WEAK ACTIVITY
79	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE C	WEAK ACTIVITY
80	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE D	WEAK ACTIVITY
81	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE D	WEAK ACTIVITY
82	PROTEIN TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE D	WEAK ACTIVITY
83	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE D	WEAK ACTIVITY
84	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE D	WEAK ACTIVITY
85	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE D	INACTIVE
86	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE D	WEAK ACTIVITY
87	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PAECILOQUINONE D	WEAK ACTIVITY

Citation 105662

Citation Details

Summary

Organisms and Their Experiments (2)

Unknown organism

Unknown organism

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