Citation 111459

KUPCHAN,SM: LACADIE,JA: HOWIE,GA: SICKLES,BR:. (1976). STRUCTURAL REQUIREMENTS FOR BIOLOGICAL ACTIVITY AMONG ANTILEUKEMIC GLAUCARUBOLONE ESTER QUASSINOIDS.. 19()

Citation Details

Title	STRUCTURAL REQUIREMENTS FOR BIOLOGICAL ACTIVITY AMONG ANTILEUKEMIC GLAUCARUBOLONE ESTER QUASSINOIDS.
Authors	KUPCHAN,SM: LACADIE,JA: HOWIE,GA: SICKLES,BR:
Year	1976
Volume	19
Issue

Summary

Year: 1976

Journal: Unknown

Organisms and Their Experiments (14)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,DIHYDRO:	INACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,DIHYDRO:	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,DIHYDRO:	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,DIHYDRO:	INACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,DIHYDRO:	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,DIHYDRO:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE,DIHYDRO: 15-BENZOATE	INACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE,DIHYDRO: 15-BENZOATE	INACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE,DIHYDRO: 15-BENZOATE	INACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE,DIHYDRO: 15-BENZOATE	INACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE,DIHYDRO: 15-BENZOATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE	INACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE	INACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE	INACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE	INACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE	INACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-BENZOATE	INACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-BENZOATE	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-BENZOATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-BENZOATE	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-BENZOATE	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-BENZOATE	ACTIVE
7	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-BENZOATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-TIGLATE	INACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-TIGLATE	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-TIGLATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-TIGLATE	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-TIGLATE	INACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-TIGLATE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,2'-ACETYL:	INACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,2'-ACETYL:	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,2'-ACETYL:	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,2'-ACETYL:	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,2'-ACETYL:	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AILANTHINONE	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AILANTHINONE	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AILANTHINONE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AILANTHINONE	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AILANTHINONE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE	INACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,DIHYDRO:	INACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE,DIHYDRO: 15-BENZOATE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-BENZOATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBOLONE-15-TIGLATE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE,2'-ACETYL:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AILANTHINONE	ACTIVE

Pierreodendron kerstingii (SIMAROUBACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OFSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEQUANTITATIVE DATAYIELD IS MORE THAN 100 MGM	GLAUCARUBINONE	None
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GLAUCARUBINONE	ACTIVE

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