EVALUATION OF MARINE SPONGE METABOLITES FOR CYTOTOXICITY AND SIGNAL TRANSDUCTION ACTIVITY.

Title	EVALUATION OF MARINE SPONGE METABOLITES FOR CYTOTOXICITY AND SIGNAL TRANSDUCTION ACTIVITY.
Authors	LONGLEY,RE: MC CONNELL,OJ: ESSICH,E: HARMODY,D:
Year	1993
Volume	56
Issue	6

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	LATRUNCULIN A	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	LATRUNCULIN A	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	LATRUNCULIN A	WEAK ACTIVITY
4	CELL ADHESION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	LATRUNCULIN A	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	LATRUNCULIN A	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	BATZELLINE A	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BATZELLINE A	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BATZELLINE A	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BATZELLINE A	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHONDRILLIN	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CHONDRILLIN	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CHONDRILLIN	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CHONDRILLIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AUREOL#	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AUREOL#	WEAK ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AUREOL#	INACTIVE
4	CELL ADHESION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AUREOL#	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	HIPPURISTANOL,EPI:	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	HIPPURISTANOL,EPI:	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	HIPPURISTANOL,EPI:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	THEONELLAMINE B	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	THEONELLAMINE B	WEAK ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	THEONELLAMINE B	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DISCORHABDIN A	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DISCORHABDIN A	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DISCORHABDIN A	ACTIVE
4	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	DISCORHABDIN A	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DISCORHABDIN C	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DISCORHABDIN C	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DISCORHABDIN C	ACTIVE
4	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	DISCORHABDIN C	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	KABIRAMIDE C	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	KABIRAMIDE C	ACTIVE
3	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	KABIRAMIDE C	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AAPTAMINE,DEMETHYL-OXY:	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AAPTAMINE,DEMETHYL-OXY:	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AAPTAMINE,DEMETHYL-OXY:	ACTIVE
4	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	AAPTAMINE,DEMETHYL-OXY:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DERCITIN	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DERCITIN	ACTIVE
3	CELL ADHESION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	DERCITIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MERIDINE	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MERIDINE	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MERIDINE	ACTIVE
4	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	MERIDINE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE C	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE C	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE C	ACTIVE
4	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	MANZAMINE C	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AMPHILECTENE FORMAMIDE	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AMPHILECTENE FORMAMIDE	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AMPHILECTENE FORMAMIDE	WEAK ACTIVITY
4	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHILECTENE FORMAMIDE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TOPSENTIN,4-5-DIHYDRO: 6''-DEOXY-BROMO:	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TOPSENTIN,4-5-DIHYDRO: 6''-DEOXY-BROMO:	WEAK ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TOPSENTIN,4-5-DIHYDRO: 6''-DEOXY-BROMO:	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	SPONGIADIOL,EPI:	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	SPONGIADIOL,EPI:	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	SPONGIADIOL,EPI:	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	SPONGIADIOL,ISO:	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	SPONGIADIOL,ISO:	WEAK ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	SPONGIADIOL,ISO:	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE A	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE A	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE A	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE B	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE B	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MANZAMINE B	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PUUPEPEHENONE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PUUPEPEHENONE	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	PUUPEPEHENONE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	REISWIGIN A	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	REISWIGIN A	WEAK ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	REISWIGIN A	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CELL ADHESION STIMULATION	PHARMACOLOGY OF COMPOUND - IN VITRO	AAPTAMINE,DEMETHYL:	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AAPTAMINE,DEMETHYL:	WEAK ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AAPTAMINE,DEMETHYL:	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AAPTAMINE,DEMETHYL:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AMPHILECT-11(20)-ENE,8-15-DIISOCYANO:	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AMPHILECT-11(20)-ENE,8-15-DIISOCYANO:	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AMPHILECT-11(20)-ENE,8-15-DIISOCYANO:	ACTIVE

Citation 121603

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