Citation 124307

PENGSUPARP,T: CAI,L: FONG,HHHS: KINGHORN,AD: PEZZUTO,JM: WANI,MC: WALL,ME:. (1994). PENTACYCLIC TRITERPENES DERIVED FROM MAPROUNEA AFRICANA ARE POTENT INHIBITOR OF HIV-1 REVERSE TRANSCRIPTASE.. 57(3)

Citation Details

Title	PENTACYCLIC TRITERPENES DERIVED FROM MAPROUNEA AFRICANA ARE POTENT INHIBITOR OF HIV-1 REVERSE TRANSCRIPTASE.
Authors	PENGSUPARP,T: CAI,L: FONG,HHHS: KINGHORN,AD: PEZZUTO,JM: WANI,MC: WALL,ME:
Year	1994
Volume	57
Issue	3

Summary

Year: 1994

Journal: Unknown

Organisms and Their Experiments (5)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID ACETATE	EQUIVOCAL
2	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID ACETATE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID	WEAK ACTIVITY
2	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID,2-ALPHA-HYDROXY:	ACTIVE
2	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID,2-ALPHA-HYDROXY:	WEAK ACTIVITY

Maprounea africana (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FORISOLATION AND IDENTIFICATION OFMASS-SPECTRAL FRAGMENTATION REPORTEDQUANTITATIVE DATA	MAPROUNIC ACID,1-BETA-HYDROXY: 3-PARA-HYDROXY-BENZOATE	None
2	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID,1-BETA-HYDROXY: 3-PARA-HYDROXY-BENZOATE	ACTIVE
3	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID,1-BETA-HYDROXY: 3-PARA-HYDROXY-BENZOATE	WEAK ACTIVITY
4	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	MAPROUNIC ACID,2-ALPHA-HYDROXY: 2-3-BIS-PARA-HYDROXY-BENZOATE	None
5	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID,2-ALPHA-HYDROXY: 2-3-BIS-PARA-HYDROXY-BENZOATE	ACTIVE
6	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID,2-ALPHA-HYDROXY: 2-3-BIS-PARA-HYDROXY-BENZOATE	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID,1-BETA-HYDROXY:	ACTIVE
2	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAPROUNIC ACID,1-BETA-HYDROXY:	WEAK ACTIVITY

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