Citation 126322

CONSTANTINOU,A: MEHTA,R: RUNYAN,C: RAO,K: VAUGHAN,A: MOON,R:. (1995). FLAVONOIDS AS DNA TOPOISOMERASE ANTAGONISTS AND POISONS: STRUCTURE-ACTIVITY RELATIONSHIPS.. 58(2)

Citation Details

Title	FLAVONOIDS AS DNA TOPOISOMERASE ANTAGONISTS AND POISONS: STRUCTURE-ACTIVITY RELATIONSHIPS.
Authors	CONSTANTINOU,A: MEHTA,R: RUNYAN,C: RAO,K: VAUGHAN,A: MOON,R:
Year	1995
Volume	58
Issue	2

Summary

Year: 1995

Journal: Unknown

Organisms and Their Experiments (9)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MYRICETIN	ACTIVE
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MYRICETIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	ACTIVE
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FISETIN	ACTIVE
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FISETIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MORIN	WEAK ACTIVITY
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MORIN	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	KAEMPFEROL	INACTIVE
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	KAEMPFEROL	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PHLORETIN	INACTIVE
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PHLORETIN	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENISTEIN	INACTIVE
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENISTEIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FLAVONE,ISO: 4'-6-7-TRIHYDROXY:	INACTIVE
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FLAVONE,ISO: 4'-6-7-TRIHYDROXY:	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE I INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FLAVONE,5-HYDROXY:FLAVONE,6-HYDROXY:PRUNETINRUTINFLAVONE,ISO: 3'-4'-7-TRIHYDROXY:FLAVONE,3-HYDROXY:APIGENINCATECHIN,(+):FLAVONE,7-HYDROXY:FLAVONEGALANGINDAIDZEIN	INACTIVE
2	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FLAVONE,5-HYDROXY:FLAVONE,6-HYDROXY:PRUNETINRUTINFLAVONE,ISO: 3'-4'-7-TRIHYDROXY:FLAVONE,3-HYDROXY:APIGENINCATECHIN,(+):FLAVONE,7-HYDROXY:FLAVONEGALANGINDAIDZEIN	INACTIVE

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