Citation 12740

BUTTERWECK,V: NAHRSTEDT,A: EVANS,J: HUFEISEN,S: RAUSER,L: SAVAGE,J: POPADAK,B: ERNSBERGER,P: ROTH,BL:. (2002). IN VITRO RECEPTOR SCREENING OF PURE CONSTITUENTS OF ST. JOHN'S WORT REVEALS NOVEL INTERACTIONS WITH A NUMBER OF GPCRS.. 162(2)

Citation Details

Title	IN VITRO RECEPTOR SCREENING OF PURE CONSTITUENTS OF ST. JOHN'S WORT REVEALS NOVEL INTERACTIONS WITH A NUMBER OF GPCRS.
Authors	BUTTERWECK,V: NAHRSTEDT,A: EVANS,J: HUFEISEN,S: RAUSER,L: SAVAGE,J: POPADAK,B: ERNSBERGER,P: ROTH,BL:
Year	2002
Volume	162
Issue	2

Summary

Year: 2002

Journal: Unknown

Organisms and Their Experiments (1)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	INACTIVE
2	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	INACTIVE
3	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	INACTIVE
4	ADRENERGIC RECEPTOR(ALPHA-2) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	INACTIVE
5	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	INACTIVE
6	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	EQUIVOCAL
7	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	EQUIVOCAL
8	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	INACTIVE
9	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	EQUIVOCAL
10	HISTAMINE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	EQUIVOCAL
11	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN,ISO:	EQUIVOCAL
12	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	EQUIVOCAL
13	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	EQUIVOCAL
14	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	EQUIVOCAL
15	ANTISIALAGOGUE EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	EQUIVOCAL
16	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	INACTIVE
17	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	EQUIVOCAL
18	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	EQUIVOCAL
19	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	EQUIVOCAL
20	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	INACTIVE
21	HISTAMINE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	WEAK ACTIVITY
22	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCITRIN	EQUIVOCAL
23	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
24	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	ACTIVE
25	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
26	ADRENERGIC RECEPTOR(ALPHA-2) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
27	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
28	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
29	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
30	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
31	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
32	HISTAMINE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
33	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	EQUIVOCAL
34	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
35	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
36	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
37	ADRENERGIC RECEPTOR(ALPHA-2) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	ACTIVE
38	ADRENERGIC RECEPTOR(BETA) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	INACTIVE
39	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
40	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	ACTIVE
41	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
42	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
43	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
44	HISTAMINE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
45	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUTIN	EQUIVOCAL
46	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
47	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
48	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
49	ADRENERGIC RECEPTOR(ALPHA-2) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	ACTIVE
50	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
51	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
52	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
53	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
54	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
55	HISTAMINE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
56	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPEROSIDE	EQUIVOCAL
57	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	ACTIVE
58	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	ACTIVE
59	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	ACTIVE
60	ADRENERGIC RECEPTOR(ALPHA-2) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	EQUIVOCAL
61	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	INACTIVE
62	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	EQUIVOCAL
63	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	ACTIVE
64	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	ACTIVE
65	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	EQUIVOCAL
66	HISTAMINE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	INACTIVE
67	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AMENTOFLAVONE	EQUIVOCAL
68	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	EQUIVOCAL
69	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	ACTIVE
70	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	EQUIVOCAL
71	ADRENERGIC RECEPTOR(ALPHA-2) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	EQUIVOCAL
72	ADRENERGIC RECEPTOR(BETA) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	EQUIVOCAL
73	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	INACTIVE
74	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	EQUIVOCAL
75	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	INACTIVE
76	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	INACTIVE
77	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	INACTIVE
78	HISTAMINE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	INACTIVE
79	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN,PSEUDO:	INACTIVE
80	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	EQUIVOCAL
81	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	ACTIVE
82	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	INACTIVE
83	ADRENERGIC RECEPTOR(ALPHA-2) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	EQUIVOCAL
84	ADRENERGIC RECEPTOR(BETA) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	ACTIVE
85	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	EQUIVOCAL
86	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	EQUIVOCAL
87	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	EQUIVOCAL
88	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	INACTIVE
89	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	INACTIVE
90	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERFORIN	EQUIVOCAL
91	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERFORIN	ACTIVE
92	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERFORIN	WEAK ACTIVITY
93	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERFORIN	EQUIVOCAL
94	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERFORIN	ACTIVE
95	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERFORIN	INACTIVE
96	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERFORIN	INACTIVE
97	SEROTONIN (5-HT) RECEPTOR BINDING DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL
98	RECEPTOR BINDING(DOPAMINE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL
99	OPIATE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL
100	ADRENERGIC RECEPTOR(ALPHA-2) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	ACTIVE
101	ADRENERGIC RECEPTOR(ALPHA-1) RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL
102	ACH RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	ACTIVE
103	GABA RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL
104	TRANSPORTER RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL
105	RECEPTOR BINDING(GLUTAMATE) DECREASED	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL
106	HISTAMINE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL
107	PEPTIDE RECEPTOR BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MIQUELIANIN	EQUIVOCAL

Citation 12740

Citation Details

Summary

Organisms and Their Experiments (1)

Unknown organism

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