Citation 127426

FREW,T: POWIS,G: BERGGREN,M: ABRAHAM,RT: ASHENDEI,CL: ZALKOW,LH: HUDSON,C: OAZIA,S: GRUSZECKA-KOWALIK,E: MERRIMAN,R: BONJOUKLIAN,R:. (1994). A MULTIWELL ASSAY FOR INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE AND THE IDENTIFICATION OF NATURAL PRODUCT INHIBITORS.. 14(6B)

Citation Details

Title	A MULTIWELL ASSAY FOR INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE AND THE IDENTIFICATION OF NATURAL PRODUCT INHIBITORS.
Authors	FREW,T: POWIS,G: BERGGREN,M: ABRAHAM,RT: ASHENDEI,CL: ZALKOW,LH: HUDSON,C: OAZIA,S: GRUSZECKA-KOWALIK,E: MERRIMAN,R: BONJOUKLIAN,R:
Year	1994
Volume	14
Issue	6B

Summary

Year: 1994

Journal: Unknown

Organisms and Their Experiments (5)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PHOSPHOKINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	ACTIVE
2	TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	EMODIN	INACTIVE
4	PHOSPHATIDYLINOSITOL 3-KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	ACTIVE
5	PHOSPHOKINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	ACTIVE
6	TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	ACTIVE
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	HYPERICIN	WEAK ACTIVITY
8	PHOSPHATIDYLINOSITOL 3-KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HYPERICIN	ACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ASPERULOSIDE	INACTIVE
10	PHOSPHATIDYLINOSITOL 3-KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ASPERULOSIDE	ACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	UTTRONIN A	INACTIVE
12	PHOSPHATIDYLINOSITOL 3-KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	UTTRONIN A	ACTIVE

Rumex crispus (POLYGONACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PHOSPHATIDYLINOSITOL 3-KINASE INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Hypericum perforatum (CLUSIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PHOSPHATIDYLINOSITOL 3-KINASE INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Galium tinctorium (RUBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PHOSPHATIDYLINOSITOL 3-KINASE INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Solanum americanum (SOLANACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PHOSPHATIDYLINOSITOL 3-KINASE INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE