Citation 13132

MI,QW: CUI,BL: CHAVEZ,D: CHAI,H: ZHU,HY: CORDELL,GA: HEDAYAT,S: KINGHORN,AD: PEZZUTO,JM:. (2002). CHARACTERIZATION OF TROPANE ALKALOID AROMATIC ESTERS THAT REVERSE THE MULTIDRUG-RESISTANCE PHENOTYPE.. 22()

Citation Details

Title	CHARACTERIZATION OF TROPANE ALKALOID AROMATIC ESTERS THAT REVERSE THE MULTIDRUG-RESISTANCE PHENOTYPE.
Authors	MI,QW: CUI,BL: CHAVEZ,D: CHAI,H: ZHU,HY: CORDELL,GA: HEDAYAT,S: KINGHORN,AD: PEZZUTO,JM:
Year	2002
Volume	22
Issue

Summary

Year: 2002

Journal: Unknown

Organisms and Their Experiments (1)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-PHENYL-ACETOXY-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	INACTIVE
2	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-PHENYL-ACETOXY-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	STRONG ACTIVITY
3	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-PHENYL-ACETOXY-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	INACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-HYDROXY-PHENYL-ACETOXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	EQUIVOCAL
5	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-HYDROXY-PHENYL-ACETOXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	ACTIVE
6	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-HYDROXY-PHENYL-ACETOXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	EQUIVOCAL
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	INACTIVE
8	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	STRONG ACTIVITY
9	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	WEAK ACTIVITY
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY)-7-BETA-HYDROXY:	INACTIVE
11	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY)-7-BETA-HYDROXY:	STRONG ACTIVITY
12	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-6-BETA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY)-7-BETA-HYDROXY:	INACTIVE
13	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-6-BETA-DI-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	ACTIVE
14	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-6-BETA-DI-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	STRONG ACTIVITY
15	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-6-BETA-DI-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	WEAK ACTIVITY
16	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-6-BETA-DI-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY)-7-BETA-HYDROXY:	WEAK ACTIVITY
17	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-6-BETA-DI-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY)-7-BETA-HYDROXY:	STRONG ACTIVITY
18	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,3-ALPHA-6-BETA-DI-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY)-7-BETA-HYDROXY:	WEAK ACTIVITY
19	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE-3-ALPHA-6-BETA-7-BETA-TRIOL-3-PHENYL-ACETATE	INACTIVE
20	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE-3-ALPHA-6-BETA-7-BETA-TRIOL-3-PHENYL-ACETATE	INACTIVE
21	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE-3-ALPHA-6-BETA-7-BETA-TRIOL-3-PHENYL-ACETATE	INACTIVE
22	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPAN-3-ALPHA-YL,1-ALPHA-(H)-5-ALPHA-(H): 3-4-5-TRIMETHOXY-BENZOATE	INACTIVE
23	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPAN-3-ALPHA-YL,1-ALPHA-(H)-5-ALPHA-(H): 3-4-5-TRIMETHOXY-BENZOATE	INACTIVE
24	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPAN-3-ALPHA-YL,1-ALPHA-(H)-5-ALPHA-(H): 3-4-5-TRIMETHOXY-BENZOATE	INACTIVE
25	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	EQUIVOCAL
26	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	STRONG ACTIVITY
27	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	WEAK ACTIVITY
28	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,7-BETA-ACETOXY-6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	EQUIVOCAL
29	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,7-BETA-ACETOXY-6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	ACTIVE
30	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE,7-BETA-ACETOXY-6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	WEAK ACTIVITY
31	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPAN-7-BETA-OL,6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	EQUIVOCAL
32	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPAN-7-BETA-OL,6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	WEAK ACTIVITY
33	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPAN-7-BETA-OL,6-BETA-BENZOYL-OXY-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	WEAK ACTIVITY
34	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE-7-BETA-OL,6-BETA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	INACTIVE
35	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE-7-BETA-OL,6-BETA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	INACTIVE
36	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TROPANE-7-BETA-OL,6-BETA-(3-4-5-TRIMETHOXY-BENZOYL-OXY)-3-ALPHA-(3-4-5-TRIMETHOXY-CINNAMOYL-OXY):	INACTIVE

Citation 13132

Citation Details

Summary

Organisms and Their Experiments (1)

Unknown organism

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