Citation 141703

EAGLING,VA: PROFIT,L: BACK,DJ:. (1999). INHIBITION OF THE CYP3A4-MEDIATED METABOLISM AND P-GLYCOPROTEIN-MEDIATED TRASPORT OF THE HIV-1 PROTEASE INHIBITOR SAQUINAVIR BY GRAPEFRUIT JUICE COMPONENTS.. 48(4)

Citation Details

Title	INHIBITION OF THE CYP3A4-MEDIATED METABOLISM AND P-GLYCOPROTEIN-MEDIATED TRASPORT OF THE HIV-1 PROTEASE INHIBITOR SAQUINAVIR BY GRAPEFRUIT JUICE COMPONENTS.
Authors	EAGLING,VA: PROFIT,L: BACK,DJ:
Year	1999
Volume	48
Issue	4

Summary

Year: 1999

Journal: Unknown

Organisms and Their Experiments (1)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME P450 INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	INACTIVE
2	TRANSPORT INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUERCETIN	INACTIVE
3	CYTOCHROME P450 INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	BERGAMOTTIN	ACTIVE
4	TRANSPORT INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	BERGAMOTTIN	INACTIVE
5	CYTOCHROME P450 INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	BERGAMOTTIN,6'-7'-DIHYDROXY:	ACTIVE
6	TRANSPORT INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	BERGAMOTTIN,6'-7'-DIHYDROXY:	ACTIVE
7	CYTOCHROME P450 INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	NARINGENIN	INACTIVE
8	TRANSPORT INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	NARINGENIN	INACTIVE
9	CYTOCHROME P450 INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	NARINGIN	INACTIVE
10	TRANSPORT INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	NARINGIN	ACTIVE

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