Citation 142871

KIM,DSHL: KOONCHANOK,NM: GEAHLEN,RL:. (1997). STRUCTURE ACTIVITY RELATIONSHIP STUDY OF EMODIN DERIVATIVES BASED ON THE PROTEIN-TYROSINE KINASE AND PROTEIN KINASE C INHIBITORY ACTIVITIES AND CYTOTOXICITY.. 10(3)

Citation Details

Title	STRUCTURE ACTIVITY RELATIONSHIP STUDY OF EMODIN DERIVATIVES BASED ON THE PROTEIN-TYROSINE KINASE AND PROTEIN KINASE C INHIBITORY ACTIVITIES AND CYTOTOXICITY.
Authors	KIM,DSHL: KOONCHANOK,NM: GEAHLEN,RL:
Year	1997
Volume	10
Issue	3

Summary

Year: 1997

Journal: Unknown

Organisms and Their Experiments (1)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	SYNTHESIS OF ANALOGS	EMODIN	None
2	TYROSINE PROTEIN KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	ACTIVE
3	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	WEAK ACTIVITY
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	ACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	ACTIVE
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN	ACTIVE
7	Not specified	COMPLETE SYNTHESIS REPORTED	CITREOROSEIN	None
8	TYROSINE PROTEIN KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CITREOROSEIN	WEAK ACTIVITY
9	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CITREOROSEIN	INACTIVE
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CITREOROSEIN	ACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CITREOROSEIN	ACTIVE
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CITREOROSEIN	WEAK ACTIVITY
13	Not specified	COMPLETE SYNTHESIS REPORTED	PHYSCION	None
14	TYROSINE PROTEIN KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PHYSCION	INACTIVE
15	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PHYSCION	INACTIVE
16	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PHYSCION	EQUIVOCAL
17	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PHYSCION	INACTIVE
18	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PHYSCION	EQUIVOCAL
19	Not specified	COMPLETE SYNTHESIS REPORTED	FALLACINAL	None
20	TYROSINE PROTEIN KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FALLACINAL	INACTIVE
21	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FALLACINAL	INACTIVE
22	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	FALLACINAL	INACTIVE
23	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	FALLACINAL	INACTIVE
24	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	FALLACINAL	INACTIVE
25	Not specified	COMPLETE SYNTHESIS REPORTED	EMODIN ANTHRONE	None
26	TYROSINE PROTEIN KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN ANTHRONE	INACTIVE
27	PROTEIN KINASE C INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN ANTHRONE	INACTIVE
28	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN ANTHRONE	ACTIVE
29	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN ANTHRONE	ACTIVE
30	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EMODIN ANTHRONE	STRONG ACTIVITY
31	Not specified	COMPLETE SYNTHESIS REPORTED	EMODIC ACID	None

Citation 142871

Citation Details

Summary

Organisms and Their Experiments (1)

Unknown organism

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