DISCOVERY OF NOVEL INDUCERS OF CELLULAR DIFFERENTIATION USING HL-60 PROMYELOCYTIC CELLS.

Title	DISCOVERY OF NOVEL INDUCERS OF CELLULAR DIFFERENTIATION USING HL-60 PROMYELOCYTIC CELLS.
Authors	MATA-GREENWOOD,E: ITO,A: WESTENBURG,H: GUL,B: MEHTA,RG: KINGHORN,AD: PEZZUTO,JM:
Year	2001
Volume	21
Issue	3B

Aglaia ponapensis (MELIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
4	Not specified	ISOLATION AND IDENTIFICATION OF	ROCAGLATE,METHYL:	None
5	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	ROCAGLATE,METHYL:	INACTIVE
6	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ROCAGLATE,METHYL:	WEAK ACTIVITY
7	Not specified	ISOLATION AND IDENTIFICATION OF	ROCAGLAMIDE	None
8	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	ROCAGLAMIDE	INACTIVE
9	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ROCAGLAMIDE	WEAK ACTIVITY
10	Not specified	ISOLATION AND IDENTIFICATION OF	ROCAGLAMIDE,DEMETHYL:	None
11	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	ROCAGLAMIDE,DEMETHYL:	ACTIVE
12	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ROCAGLAMIDE,DEMETHYL:	ACTIVE

Amomum coccineum (ZINGIBERACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Asarum canadense (ARISTOLOCHIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Calophyllum longifolium (CLUSIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE

Casimiroa edulis (RUTACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
4	Not specified	ISOLATION AND IDENTIFICATION OF	ZAPOTIN	None
5	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	ZAPOTIN	ACTIVE
6	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ZAPOTIN	WEAK ACTIVITY
7	Not specified	ISOLATION AND IDENTIFICATION OF	FLAVONE,2'-5-6-TRIMETHOXY:	None
8	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	FLAVONE,2'-5-6-TRIMETHOXY:	ACTIVE
9	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FLAVONE,2'-5-6-TRIMETHOXY:	ACTIVE
10	Not specified	ISOLATION AND IDENTIFICATION OF	PHELLOPTERIN	None
11	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	PHELLOPTERIN	INACTIVE
12	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PHELLOPTERIN	EQUIVOCAL
13	Not specified	ISOLATION AND IDENTIFICATION OF	PIMPINELLIN,ISO:	None
14	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	PIMPINELLIN,ISO:	INACTIVE
15	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PIMPINELLIN,ISO:	INACTIVE
16	Not specified	ISOLATION AND IDENTIFICATION OF	CASIMIROIN	None
17	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	CASIMIROIN	INACTIVE
18	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CASIMIROIN	ACTIVE
19	Not specified	ISOLATION AND IDENTIFICATION OF	QUINOLIN-2-(1H)-ONE,4-METHOXY-1-METHYL:	None
20	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUINOLIN-2-(1H)-ONE,4-METHOXY-1-METHYL:	INACTIVE
21	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUINOLIN-2-(1H)-ONE,4-METHOXY-1-METHYL:	EQUIVOCAL
22	Not specified	ISOLATION AND IDENTIFICATION OF	QUINOL-4-ONE,5-HYDROXY-1-METHYL-2-PHENYL:	None
23	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUINOL-4-ONE,5-HYDROXY-1-METHYL-2-PHENYL:	INACTIVE
24	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	QUINOL-4-ONE,5-HYDROXY-1-METHYL-2-PHENYL:	EQUIVOCAL
25	Not specified	ISOLATION AND IDENTIFICATION OF	FAGARINE,GAMMA:	None
26	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	FAGARINE,GAMMA:	INACTIVE

Chromolaena odorata (ASTERACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Croton argyratus (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Croton caryocarpus (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Croton lechleri (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Croton rigidus (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Daphnopsis philippiana (THYMELAEACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Deinbollia pinnata (SAPINDACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE

Deutzianthus tonkinensis (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Didiplis diandra (LYTHRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Diospyros sericea (EBENACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL

Ditta myricoides (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Euonymus bungeanus (CELASTRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Egeria densa (HYDROCHARITACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Ficus species (MORACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Gymnacranthera species (MYRISTICACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Gymnocoronis spilanthoides (ASTERACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE

Hyptis capitata (LAMIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Limnophila indica (SCROPHULARIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	WEAK ACTIVITY

Macaranga triloba (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Maprounea membranacea (EUPHORBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE

Nomaphila stricta (ACANTHACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Palicourea padifolia (RUBIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Petiveria alliacea (PHYTOLACCACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
4	Not specified	ISOLATION AND IDENTIFICATION OF	TRISULFIDE,DIBENZYL:	None
5	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	TRISULFIDE,DIBENZYL:	ACTIVE
6	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TRISULFIDE,DIBENZYL:	INACTIVE
7	Not specified	ISOLATION AND IDENTIFICATION OF	DISULFANYL-1-ETHANOL,2-BENZYL:	None
8	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	DISULFANYL-1-ETHANOL,2-BENZYL:	ACTIVE
9	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	DISULFANYL-1-ETHANOL,2-BENZYL:	INACTIVE
10	Not specified	ISOLATION AND IDENTIFICATION OF	PHYTOL	None
11	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	PHYTOL	INACTIVE
12	Not specified	ISOLATION AND IDENTIFICATION OF	ARBORINOL,ISO:	None
13	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITRO	ARBORINOL,ISO:	INACTIVE

Pometia pinnata (SAPINDACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CARCINOGENESIS INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Tithonia diversifolia (ASTERACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Vernonia officinalis (ASTERACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Witheringia solanacea (SOLANACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CELL DIFFERENTIATION INDUCTION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE

Citation 146331

Citation Details

Summary

Organisms and Their Experiments (32)

Aglaia ponapensis (MELIACEAE)

Amomum coccineum (ZINGIBERACEAE)

Asarum canadense (ARISTOLOCHIACEAE)

Calophyllum longifolium (CLUSIACEAE)

Casimiroa edulis (RUTACEAE)

Chromolaena odorata (ASTERACEAE)

Croton argyratus (EUPHORBIACEAE)

Croton caryocarpus (EUPHORBIACEAE)

Croton lechleri (EUPHORBIACEAE)

Croton rigidus (EUPHORBIACEAE)

Daphnopsis philippiana (THYMELAEACEAE)

Deinbollia pinnata (SAPINDACEAE)

Deutzianthus tonkinensis (EUPHORBIACEAE)

Didiplis diandra (LYTHRACEAE)

Diospyros sericea (EBENACEAE)

Ditta myricoides (EUPHORBIACEAE)

Euonymus bungeanus (CELASTRACEAE)

Egeria densa (HYDROCHARITACEAE)

Ficus species (MORACEAE)

Gymnacranthera species (MYRISTICACEAE)

Gymnocoronis spilanthoides (ASTERACEAE)

Hyptis capitata (LAMIACEAE)

Limnophila indica (SCROPHULARIACEAE)

Macaranga triloba (EUPHORBIACEAE)

Maprounea membranacea (EUPHORBIACEAE)

Nomaphila stricta (ACANTHACEAE)

Palicourea padifolia (RUBIACEAE)

Petiveria alliacea (PHYTOLACCACEAE)

Pometia pinnata (SAPINDACEAE)

Tithonia diversifolia (ASTERACEAE)

Vernonia officinalis (ASTERACEAE)

Witheringia solanacea (SOLANACEAE)

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