Citation 152358

LUESCH,H: MOORE,RE: PAUL,V: MOOBERRY,SL: CORBETT,TH:. (2001). ISOLATION OF DOLASTATIN 10 FROM THE MARINE CYANOBACTERIUM SYMPLOCA SPECIES VP642 AND TOTAL STEREOCHEMISTRY AND BIOLOGICAL EVALUATION OF TIS ANALOGUE SYMPLOSTATIN 1.. 64(7)

Citation Details

Title	ISOLATION OF DOLASTATIN 10 FROM THE MARINE CYANOBACTERIUM SYMPLOCA SPECIES VP642 AND TOTAL STEREOCHEMISTRY AND BIOLOGICAL EVALUATION OF TIS ANALOGUE SYMPLOSTATIN 1.
Authors	LUESCH,H: MOORE,RE: PAUL,V: MOOBERRY,SL: CORBETT,TH:
Year	2001
Volume	64
Issue	7

Summary

Year: 2001

Journal: Unknown

Organisms and Their Experiments (2)

Symploca species (OSCILLATORIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	UV SPECTRUM GIVEN FORISOLATION AND IDENTIFICATION OFMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTED	DOLASTATIN 10	None
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
13	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVO	None	ACTIVE
14	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVO	None	ACTIVE
15	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	DOLASTATIN 10	STRONG ACTIVITY
16	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	DOLASTATIN 10	STRONG ACTIVITY
17	MICROTUBULE DEPOLYMERIZATION	PHARMACOLOGY OF COMPOUND - IN VITRO	DOLASTATIN 10	ACTIVE

Symploca hydnoides (OSCILLATORIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OF	SYMPLOSTATIN 1	None
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	SYMPLOSTATIN 1	STRONG ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	SYMPLOSTATIN 1	STRONG ACTIVITY
4	MICROTUBULE DEPOLYMERIZATION	PHARMACOLOGY OF COMPOUND - IN VITRO	SYMPLOSTATIN 1	ACTIVE
5	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	SYMPLOSTATIN 1	.
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	SYMPLOSTATIN 1	ACTIVE
7	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	SYMPLOSTATIN 1	ACTIVE
8	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	SYMPLOSTATIN 1	ACTIVE
9	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	SYMPLOSTATIN 1	ACTIVE