Citation 153768

HALL,IH: LEE,KH: EIGEBALY,SA: IMAKURA,Y: SUMIDA,Y: WU,RY:. (1979). ANTITUMOR AGENTS. XXXIV. MECHANISM OF ACTION OF BRUCEOSIDE A AND BRUSATOL ON NUCLEIC ACID METABOLISM OF P-388 LYMPHOCYTIC LEUKEMIA CELLS.. 68()

Citation Details

Title	ANTITUMOR AGENTS. XXXIV. MECHANISM OF ACTION OF BRUCEOSIDE A AND BRUSATOL ON NUCLEIC ACID METABOLISM OF P-388 LYMPHOCYTIC LEUKEMIA CELLS.
Authors	HALL,IH: LEE,KH: EIGEBALY,SA: IMAKURA,Y: SUMIDA,Y: WU,RY:
Year	1979
Volume	68
Issue

Summary

Year: 1979

Journal: Unknown

Organisms and Their Experiments (5)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEIN D	INACTIVE
2	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEIN D	WEAK ACTIVITY
3	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEIN D	ACTIVE
4	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEIN D	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEANTIN	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEANTIN	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEANTIN	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEANTIN	INACTIVE
5	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEANTIN	WEAK ACTIVITY
6	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	None	WEAK ACTIVITY
7	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	None	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUSATOL	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUSATOL	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUSATOL	ACTIVE
4	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL	ACTIVE
5	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL	ACTIVE
6	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL	ACTIVE
7	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	ACTIVE
8	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	ACTIVE
9	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	ACTIVE
10	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	INACTIVE
11	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	ACTIVE
12	DEOXYRIBONUCLEASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	ACTIVE
13	RIBONUCLEASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	ACTIVE
14	ADENOSYL METHIONINE TRANSFERASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	INACTIVE
15	ADENOSYL METHIONINE TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	INACTIVE
16	ASPARTATE CARBAMATE TRANSFERASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	INACTIVE
17	ASPARTATE CARBAMATE TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	INACTIVE
18	CARBAMYL PHOSPHATE SYNTHETASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	INACTIVE
19	CARBAMYL PHOSPHATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	INACTIVE
20	ATP-ASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	EQUIVOCAL
21	CYCLIC AMP STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	ACTIVE
22	CYCLIC AMP INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUSATOL	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEOSIDE A	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEOSIDE A	INACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEOSIDE A	INACTIVE
4	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOSIDE A	WEAK ACTIVITY
5	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOSIDE A	ACTIVE
6	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOSIDE A	ACTIVE
7	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUCEOSIDE A	ACTIVE
8	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUCEOSIDE A	ACTIVE
9	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUCEOSIDE A	ACTIVE
10	ATP-ASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUCEOSIDE A	INACTIVE
11	CYCLIC AMP INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	BRUCEOSIDE A	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEIN E	INACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	BRUCEIN E	INACTIVE
3	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEIN E	WEAK ACTIVITY
4	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEIN E	ACTIVE
5	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEIN E	ACTIVE

Citation 153768

Citation Details

Summary

Organisms and Their Experiments (5)

Unknown organism

Unknown organism

Unknown organism

Unknown organism

Unknown organism

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