Citation 159905

LIOU,YF: HALL,IH: OKANO,M: LEE,KH: CHANEY,SG:. (1982). ANTITUMOR AGENTS. XLVIII. STRUCTURE-ACTIVITY RELATIONSHIPS OF QUASSINOIDS AS IN VITRO PROTEIN SYNTHESIS INHIBITORS OF P-388 LYMPHOCYTIC LEUKEMIA TUMOR CELL METABOLISM.. 71()

Citation Details

Title	ANTITUMOR AGENTS. XLVIII. STRUCTURE-ACTIVITY RELATIONSHIPS OF QUASSINOIDS AS IN VITRO PROTEIN SYNTHESIS INHIBITORS OF P-388 LYMPHOCYTIC LEUKEMIA TUMOR CELL METABOLISM.
Authors	LIOU,YF: HALL,IH: OKANO,M: LEE,KH: CHANEY,SG:
Year	1982
Volume	71
Issue

Summary

Year: 1982

Journal: Unknown

Organisms and Their Experiments (18)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOSIDE A	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOSIDE A	ACTIVE
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOSIDE A	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL	ACTIVE
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEANTIN	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEANTIN	ACTIVE
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEANTIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL TRIACETATE	INACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL TRIACETATE	EQUIVOCAL
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL TRIACETATE	EQUIVOCAL

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE	EQUIVOCAL
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,3-(3-4-DIMETHYL-2-PENTENOYL):	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,3-(3-4-DIMETHYL-2-PENTENOYL):	INACTIVE
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,3-(3-4-DIMETHYL-2-PENTENOYL):	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BBRUCEANTIN,3-(3-4-DIMETHYL-2-PENTENOYL):	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BBRUCEANTIN,3-(3-4-DIMETHYL-2-PENTENOYL):	STRONG ACTIVITY
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BBRUCEANTIN,3-(3-4-DIMETHYL-2-PENTENOYL):	STRONG ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,12-ACETYL-3-15-DISENECIOYL:	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,12-ACETYL-3-15-DISENECIOYL:	WEAK ACTIVITY
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,12-ACETYL-3-15-DISENECIOYL:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,3-15-DISENECIOYL:	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,3-15-DISENECIOYL:	ACTIVE
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUCEOLIDE,3-15-DISENECIOYL:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS-12-12'-DIACETYL: SUCCINATE	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS-12-12'-DIACETYL: SUCCINATE	INACTIVE
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS-12-12'-DIACETYL: SUCCINATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: ADIPATE	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: ADIPATE	STRONG ACTIVITY
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: ADIPATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: GLUTARATE	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: GLUTARATE	ACTIVE
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: GLUTARATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: SUCCINATE	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: SUCCINATE	STRONG ACTIVITY
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: SUCCINATE	STRONG ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: MALONATE	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: MALONATE	STRONG ACTIVITY
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: MALONATE	STRONG ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: DIHYDRO: SUCCINATE	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: DIHYDRO: SUCCINATE	STRONG ACTIVITY
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: DIHYDRO: SUCCINATE	STRONG ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: TETRAHYDRO: SUCCINATE	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: TETRAHYDRO: SUCCINATE	EQUIVOCAL
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOLYL,BIS: TETRAHYDRO: SUCCINATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,TETRAHYDRO:	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,TETRAHYDRO:	INACTIVE
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,TETRAHYDRO:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,DIHYDRO:	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,DIHYDRO:	WEAK ACTIVITY
3	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,DIHYDRO:	ACTIVE
4	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,TETRAHYDRO: 2-DEOXO-2-HYDROXY: LACTOL	WEAK ACTIVITY
5	PROTEIN SYNTHESIS INHIBITION(ENDOGENOUS)	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,TETRAHYDRO: 2-DEOXO-2-HYDROXY: LACTOL	INACTIVE
6	POLYURIDINE-DIRECTED POLYPHENYLALANINE SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	BRUSATOL,TETRAHYDRO: 2-DEOXO-2-HYDROXY: LACTOL	WEAK ACTIVITY

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