Citation 163537

SEHGAL,SN: BAKER,H: ENG,CP: SINGH,K: VEZINA,C:. (1983). DEMETHOXYRAPAMYCIN (AY-24,668), A NEW ANTIFUNGAL ANTIBIOTIC.. 36(4)

Citation Details

Title	DEMETHOXYRAPAMYCIN (AY-24,668), A NEW ANTIFUNGAL ANTIBIOTIC.
Authors	SEHGAL,SN: BAKER,H: ENG,CP: SINGH,K: VEZINA,C:
Year	1983
Volume	36
Issue	4

Summary

Year: 1983

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN	ACTIVE
2	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN	WEAK ACTIVITY
3	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN	INACTIVE
4	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN	ACTIVE
5	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN	WEAK ACTIVITY
6	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN	INACTIVE
7	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	RAPAMYCIN	ACTIVE

Streptomyces hygroscopicus (STREPTOMYCETACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	RAPAMYCIN,27-O-DEMETHYL:	None
2	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	RAPAMYCIN,27-O-DEMETHYL:	.
3	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	RAPAMYCIN,27-O-DEMETHYL:	ACTIVE
4	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	RAPAMYCIN,27-O-DEMETHYL:	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	RAPAMYCIN,27-O-DEMETHYL:	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	RAPAMYCIN,27-O-DEMETHYL:	INACTIVE
7	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	RAPAMYCIN,27-O-DEMETHYL:	INACTIVE
8	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN,27-O-DEMETHYL:	ACTIVE
9	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN,27-O-DEMETHYL:	WEAK ACTIVITY
10	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN,27-O-DEMETHYL:	WEAK ACTIVITY
11	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN,27-O-DEMETHYL:	ACTIVE
12	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN,27-O-DEMETHYL:	EQUIVOCAL
13	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RAPAMYCIN,27-O-DEMETHYL:	INACTIVE

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