Citation 171089

WOLPERT-DEFILLIPPES,MK: ADAMSON,RH: CYSYK,RL: JOHNS,DG:. (1979). INITIAL STUDIES ON THE CYTOTOXIC ACTION OF MAYTANSINE, A NOVEL ANSA MACROLIDE.. 24()

Citation Details

Title	INITIAL STUDIES ON THE CYTOTOXIC ACTION OF MAYTANSINE, A NOVEL ANSA MACROLIDE.
Authors	WOLPERT-DEFILLIPPES,MK: ADAMSON,RH: CYSYK,RL: JOHNS,DG:
Year	1979
Volume	24
Issue

Summary

Year: 1979

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	STRONG ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	STRONG ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	STRONG ACTIVITY
4	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	ACTIVE
5	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	ACTIVE
6	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	WEAK ACTIVITY
7	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	INACTIVE
8	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	INACTIVE
9	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	ACTIVE
10	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	ACTIVE
11	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	INACTIVE
12	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	ACTIVE
13	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
14	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	LEUROCRISTINE	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	LEUROCRISTINE	ACTIVE

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