Citation 171937

MIRANDA,CL: CHEEKE,PR: BUHLER,DR:. (1980). COMPARATIVE EFFECTS OF THE PYRROLIZIDINE ALKALOIDS JACOBINE AND MONOCROTALINE ON HEPATIC DRUG METABOLIZING ENZYMES IN THE RAT.. 29(3)

Citation Details

Title	COMPARATIVE EFFECTS OF THE PYRROLIZIDINE ALKALOIDS JACOBINE AND MONOCROTALINE ON HEPATIC DRUG METABOLIZING ENZYMES IN THE RAT.
Authors	MIRANDA,CL: CHEEKE,PR: BUHLER,DR:
Year	1980
Volume	29
Issue	3

Summary

Year: 1980

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	EPOXIDE HYDRASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	JACOBINE	STRONG ACTIVITY
2	GLUTATHIONE-S-TRANSFERASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	JACOBINE	ACTIVE
3	ARYL HYDROCARBON HYDROXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	JACOBINE	ACTIVE
4	AMINOPYRINE-N-DEMETHYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	JACOBINE	ACTIVE
5	CYTOCHROME OXIDASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	JACOBINE	WEAK ACTIVITY
6	AMINOPYRINE-N-DEMETHYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	JACOBINE	INACTIVE
7	AMINOPYRINE-N-DEMETHYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	JACOBINE	INACTIVE
8	ARYL HYDROCARBON HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	JACOBINE	INACTIVE
9	ARYL HYDROCARBON HYDROXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	JACOBINE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME OXIDASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	MONOCROTALINE	WEAK ACTIVITY
2	AMINOPYRINE-N-DEMETHYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	MONOCROTALINE	ACTIVE
3	ARYL HYDROCARBON HYDROXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	MONOCROTALINE	ACTIVE
4	EPOXIDE HYDRASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	MONOCROTALINE	INACTIVE
5	GLUTATHIONE-S-TRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	MONOCROTALINE	ACTIVE
6	ARYL HYDROCARBON HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MONOCROTALINE	INACTIVE
7	ARYL HYDROCARBON HYDROXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MONOCROTALINE	INACTIVE
8	AMINOPYRINE-N-DEMETHYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MONOCROTALINE	WEAK ACTIVITY

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