Citation 172394

HALL,IH: KASAI,R: WU,RY: TAGAHARA,K: LEE,KH:. (1982). ANTITUMOR AGENTS LV: EFFECTS OF GENKWADAPHNIN AND YUANHUACINE ON NUCLEIC ACID SYNTHESIS OF P-388 LYMPHOCYTIC LEUKEMIA CELLS.. 71()

Citation Details

Title	ANTITUMOR AGENTS LV: EFFECTS OF GENKWADAPHNIN AND YUANHUACINE ON NUCLEIC ACID SYNTHESIS OF P-388 LYMPHOCYTIC LEUKEMIA CELLS.
Authors	HALL,IH: KASAI,R: WU,RY: TAGAHARA,K: LEE,KH:
Year	1982
Volume	71
Issue

Summary

Year: 1982

Journal: Unknown

Organisms and Their Experiments (1)

Daphne genkwa (THYMELAEACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	VOUCHER SPECIMEN REPORTED FORPHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
2	Not specified	VOUCHER SPECIMEN REPORTED FORUV SPECTRUM GIVEN FORISOLATION AND IDENTIFICATION OFQUANTITATIVE DATAMARKER CODE - FERTILITY REGULATION. NO RETRIEVABLE DATA	YUANHUACINE	None
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	YUANHUACINE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	YUANHUACINE	ACTIVE
5	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	ACTIVE
6	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
7	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
8	C-14 FORMATE INCORPORATION INTO PURINES INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	ACTIVE
9	DNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	ACTIVE
10	T-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
11	R-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
12	M-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
13	CARBAMYL PHOSPHATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
14	CARBAMYL PHOSPHATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
15	ASPARTATE TRANSCARBOXAMYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
16	OROTIDINE-5'-PHOSPHATE DECARBOXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
17	THYMIDYLATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
18	THYMIDINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
19	THYMIDYLATE MONOPHOSPHATE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
20	THYMIDYLATE DIPHOSPHATE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
21	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	ACTIVE
22	INOSINIC ACID DEHYDROGENASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	ACTIVE
23	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	ACTIVE
24	RIBONUCLEOTIDE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
25	RIBONUCLEOTIDE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	YUANHUACINE	INACTIVE
26	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
27	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
28	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
29	C-14 FORMATE INCORPORATION INTO PURINES INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
30	DNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
31	T-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
32	R-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
33	M-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
34	CARBAMYL PHOSPHATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
35	ASPARTATE TRANSCARBOXAMYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
36	OROTIDINE-5'-PHOSPHATE DECARBOXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
37	THYMIDYLATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
38	THYMIDINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
39	THYMIDINE KINASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
40	OROTIDINE-5'-PHOSPHATE DECARBOXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
41	THYMIDYLATE MONOPHOSPHATE KINASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
42	THYMIDYLATE DIPHOSPHATE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
43	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
44	INOSINIC ACID DEHYDROGENASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
45	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
46	RIBONUCLEOTIDE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
47	HISTONE PHOSPHORYLATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
48	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
49	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
50	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
51	C-14 FORMATE INCORPORATION INTO PURINES INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
52	DNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
53	T-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
54	R-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
55	M-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
56	OROTIDINE-5'-PHOSPHATE DECARBOXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
57	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
58	INOSINIC ACID DEHYDROGENASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
59	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	None
60	RIBONUCLEOTIDE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	INACTIVE
61	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
62	C-14 FORMATE INCORPORATION INTO PURINES INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
63	DNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
64	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
65	INOSINIC ACID DEHYDROGENASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
66	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	YUANHUACINE	ACTIVE
68	Not specified	VOUCHER SPECIMEN REPORTED FORISOLATION AND IDENTIFICATION OF	GENKWADAPHNIN	None
69	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GENKWADAPHNIN	ACTIVE
70	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	GENKWADAPHNIN	ACTIVE
71	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	ACTIVE
72	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
73	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	ACTIVE
74	DNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	ACTIVE
75	T-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
76	R-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	ACTIVE
77	M-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
78	CARBAMYL PHOSPHATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
79	ASPARTATE TRANSCARBOXAMYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
80	OROTIDINE-5'-PHOSPHATE DECARBOXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
81	THYMIDYLATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
82	THYMIDINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
83	THYMIDYLATE MONOPHOSPHATE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
84	THYMIDYLATE DIPHOSPHATE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
85	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	ACTIVE
86	INOSINIC ACID DEHYDROGENASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	ACTIVE
87	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	ACTIVE
88	RIBONUCLEOTIDE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
89	NONHISTONE PHOSPHORYLATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	INACTIVE
90	C-14 FORMATE INCORPORATION INTO PURINES INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GENKWADAPHNIN	ACTIVE
91	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
92	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
93	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
94	C-14 FORMATE INCORPORATION INTO PURINES INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
95	DNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
96	T-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
97	R-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
98	M-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
99	CARBAMYL PHOSPHATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
100	ASPARTATE TRANSCARBOXAMYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
101	OROTIDINE-5'-PHOSPHATE DECARBOXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
102	THYMIDYLATE SYNTHETASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
103	THYMIDYLATE DIPHOSPHATE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
104	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
105	INOSINIC ACID DEHYDROGENASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
106	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
107	RIBONUCLEOTIDE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
108	HISTONE PHOSPHORYLATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
109	THYMIDINE KINASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
110	THYMIDYLATE MONOPHOSPHATE KINASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
111	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
112	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
113	PROTEIN SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
114	C-14 FORMATE INCORPORATION INTO PURINES INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
115	DNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
116	T-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
117	R-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
118	M-RNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
119	OROTIDINE-5'-PHOSPHATE DECARBOXYLASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	INACTIVE
120	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
121	INOSINIC ACID DEHYDROGENASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
122	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
123	RIBONUCLEOTIDE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
124	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
125	C-14 FORMATE INCORPORATION INTO PURINES INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
126	DNA POLYMERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
127	PHOSPHORIBOSYL PYROPHOSPHATE AMINOTRANSFERASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
128	INOSINIC ACID DEHYDROGENASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE
129	DIHYDROFOLATE REDUCTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVO	GENKWADAPHNIN	ACTIVE

Citation 172394

Citation Details

Summary

Organisms and Their Experiments (1)

Daphne genkwa (THYMELAEACEAE)

Show SPARQL Queries (1)

Query 1