Citation 173448

GORDON,WP: FORTE,AJ: MC MURTRY,RJ: GAL,J: NELSON,SD:. (1982). HEPATOTOXICITY AND PULMONARY TOXICITY OF PENNYROYAL OIL AND ITS CONSTITUENT TERPENES IN THE MOUSE.. 65()

Citation Details

Title	HEPATOTOXICITY AND PULMONARY TOXICITY OF PENNYROYAL OIL AND ITS CONSTITUENT TERPENES IN THE MOUSE.
Authors	GORDON,WP: FORTE,AJ: MC MURTRY,RJ: GAL,J: NELSON,SD:
Year	1982
Volume	65
Issue

Summary

Year: 1982

Journal: Unknown

Organisms and Their Experiments (7)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO: EPOXIDE	EQUIVOCAL
2	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO: EPOXIDE	WEAK ACTIVITY
3	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO: EPOXIDE	ACTIVE
4	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO: EPOXIDE	EQUIVOCAL
5	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO: EPOXIDE	WEAK ACTIVITY
6	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO: EPOXIDE	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PIPERITENONE	INACTIVE
2	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PIPERITENONE	EQUIVOCAL
3	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PIPERITENONE	EQUIVOCAL
4	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PIPERITENONE	EQUIVOCAL
5	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PIPERITENONE	WEAK ACTIVITY
6	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PIPERITENONE	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MENTHOFURAN	ACTIVE
2	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MENTHOFURAN	ACTIVE
3	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MENTHOFURAN	ACTIVE
4	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MENTHOFURAN	WEAK ACTIVITY
5	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MENTHOFURAN	ACTIVE
6	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MENTHOFURAN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
2	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
3	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
4	HEPATOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
5	HEPATOTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	WEAK ACTIVITY
6	GLUTAMATE-PYRUVATE-TRANSAMINASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
7	GLUTAMATE-PYRUVATE-TRANSAMINASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
8	GLUTAMATE-PYRUVATE-TRANSAMINASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
9	GLUTAMATE-PYRUVATE-TRANSAMINASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	EQUIVOCAL
10	GLUTAMATE-PYRUVATE-TRANSAMINASE STIMULATION	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	WEAK ACTIVITY
11	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
12	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
13	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
14	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	INACTIVE
15	TOXIC EFFECT(GENERAL)	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(-): (S):	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(+): (R):	ACTIVE
2	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(+): (R):	ACTIVE
3	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(+): (R):	ACTIVE
4	HEPATOTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(+): (R):	WEAK ACTIVITY
5	GLUTAMATE-PYRUVATE-TRANSAMINASE STIMULATION	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(+): (R):	WEAK ACTIVITY
6	HEPATOTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(+): (R):	ACTIVE
7	GLUTAMATE-PYRUVATE-TRANSAMINASE STIMULATION	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,(+): (R):	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO:	INACTIVE
2	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO:	ACTIVE
3	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO:	ACTIVE
4	HEPATOTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO:	WEAK ACTIVITY
5	HEPATOTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO:	WEAK ACTIVITY
6	HEPATOTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PULEGONE,ISO:	EQUIVOCAL

Mentha pulegium (LAMIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	IDENTIFICATION IN BY GC/MS	PIPERITENONEMENTHOFURANMENTHONE,ISO:CYCLOHEXANONE,3-METHYL:PULEGOLEMENTHA-1-4(8)-DIENE,PARA:PULEGONE EPOXIDEPINENE,BETA:LIMONENEPULEGONEMENTHONEPIPERITONEPULEGONE,ISO:PINENE,ALPHA:CYMENE,PARA:	None
2	TOXICITY ASSESSMENT(QUANTITATIVE)	TOXICITY MARKER CODEPHARMACOLOGY OF EXTRACT - IN VIVO	None	.
3	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF EXTRACT - IN VIVO	None	ACTIVE
4	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF EXTRACT - IN VIVO	None	ACTIVE
5	HEPATOTOXIC ACTIVITY	TOXICITY MARKER CODEPHARMACOLOGY OF EXTRACT - IN VIVO	None	STRONG ACTIVITY

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