Citation 176650

CHEN,GL: YANG,L: ROWE,TC: HALLIGAN,BD: TEWEY,KM: LIU,LF:. (1984). NONINTERCALATIVE ANTITUMOR DRUGS INTERFERE WITH THE BREAKAGE-REUNION REACTION OF MAMMALIAN DNA TOPOISOMERASE II.. 259(21)

Citation Details

Title	NONINTERCALATIVE ANTITUMOR DRUGS INTERFERE WITH THE BREAKAGE-REUNION REACTION OF MAMMALIAN DNA TOPOISOMERASE II.
Authors	CHEN,GL: YANG,L: ROWE,TC: HALLIGAN,BD: TEWEY,KM: LIU,LF:
Year	1984
Volume	259
Issue	21

Summary

Year: 1984

Journal: Unknown

Organisms and Their Experiments (3)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	PODOPHYLLOTOXIN	ACTIVE
2	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	PODOPHYLLOTOXIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ETOPOSIDE*	ACTIVE
2	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	ETOPOSIDE*	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	TENIPOSIDE*	ACTIVE
2	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	TENIPOSIDE*	ACTIVE
3	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TENIPOSIDE*	ACTIVE
4	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	TENIPOSIDE*	INACTIVE

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