Citation 178385

SHIBATA,S:. (1981). MEDICINAL CHEMISTRY OF TRITERPENOID SAPONINS AND SAPOGENINS.. 1981()

Citation Details

Title	MEDICINAL CHEMISTRY OF TRITERPENOID SAPONINS AND SAPOGENINS.
Authors	SHIBATA,S:
Year	1981
Volume	1981
Issue

Summary

Year: 1981

Journal: Unknown

Organisms and Their Experiments (14)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REDUCTASE,5-ALPHA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GLYCYRRHETINIC ACID	INACTIVE
2	REDUCTASE,5-BETA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GLYCYRRHETINIC ACID	ACTIVE
3	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	.
4	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	.
5	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	INACTIVE
6	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	INACTIVE
7	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	INACTIVE
8	ANALGESIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	ACTIVE
9	ANTIINFLAMMATORY ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	INACTIVE
10	ANTIALLERGENIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	INACTIVE
11	ANTIALLERGENIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REDUCTASE,5-ALPHA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GLYCYRRHETINIC ACID,11-DEOXO:	INACTIVE
2	REDUCTASE,5-BETA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GLYCYRRHETINIC ACID,11-DEOXO:	ACTIVE
3	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO:	INACTIVE
4	ANALGESIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REDUCTASE,5-ALPHA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GLYCYRRHETINIC ACID,20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	ACTIVE
2	REDUCTASE,5-BETA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GLYCYRRHETINIC ACID,20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	ACTIVE
3	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	INACTIVE
4	ANALGESIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	ACTIVE
2	ANALGESIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	ACTIVE
3	ANTIINFLAMMATORY ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	WEAK ACTIVITY
4	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	.
5	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	ACTIVE
6	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	ACTIVE
7	REDUCTASE,5-ALPHA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	INACTIVE
8	REDUCTASE,5-BETA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	INACTIVE
9	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	.
10	ANTIALLERGENIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	WEAK ACTIVITY
11	ANTIALLERGENIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	INACTIVE
12	ANTIALLERGENIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	GLYCYRRHETINIC ACID,11-DEOXO-20-BETA-DECARBOXY-20-BETA-HYDROXY-METHYL:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REDUCTASE,5-ALPHA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HEDERAGENIN	ACTIVE
2	REDUCTASE,5-BETA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HEDERAGENIN	ACTIVE
3	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	HEDERAGENIN	ACTIVE
4	ANALGESIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	HEDERAGENIN	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REDUCTASE,5-ALPHA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HEDERAGENIN,11-OXO:	INACTIVE
2	REDUCTASE,5-BETA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	HEDERAGENIN,11-OXO:	INACTIVE
3	ANALGESIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	HEDERAGENIN,11-OXO:	ACTIVE
4	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	HEDERAGENIN,11-OXO:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REDUCTASE,5-ALPHA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OLEANOLIC ACID	INACTIVE
2	REDUCTASE,5-BETA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OLEANOLIC ACID	INACTIVE
3	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	OLEANOLIC ACID	INACTIVE
4	ANALGESIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	OLEANOLIC ACID	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REDUCTASE,5-ALPHA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OLEANOLIC ACID,11-OXO:	ACTIVE
2	REDUCTASE,5-BETA: INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OLEANOLIC ACID,11-OXO:	ACTIVE
3	ANTIULCER ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	OLEANOLIC ACID,11-OXO:	INACTIVE
4	ANALGESIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	OLEANOLIC ACID,11-OXO:	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTIINFLAMMATORY ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	SAIKOSAPONIN A	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTIINFLAMMATORY ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	SAIKOSAPONIN C	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTIINFLAMMATORY ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	SAIKOSAPONIN D	ACTIVE

Bupleurum falcatum (APIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	LIVER EFFECTS(UNSPECIFIED)	MEDICINAL FOLKLORE REPORTED FOR	None	None
2	Not specified	PRESENT IN (REVIEW)	SAIKOSAPONIN CSAIKOSAPONIN ASAIKOSAPONIN D	None

Polygala tenuifolia (POLYGALACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	PRESENT IN (REVIEW)	SENEGIN IIONJISAPONIN EONJISAPONIN FONJISAPONIN GONJISAPONIN CONJISAPONIN DSENEGIN IIISENEGIN IV	None

Platycodon grandiflorum (CAMPANULACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	PRESENT IN (REVIEW)	None	None
2	EXPECTORANT ACTIVITY	MEDICINAL FOLKLORE REPORTED FOR	None	None
3	ANTITUSSIVE ACTIVITY	MEDICINAL FOLKLORE REPORTED FOR	None	None
4	Not specified	PRESENT IN (REVIEW)	PLATYCODIN APLATYCODIN CPLATYCODIN DPLATYCODIN D-2POLYGALACIN DPOLYGALACIN D-2	None

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