Citation 182158

LONG,BH: GOLIK,J: FORENZA,S: WARD,B: REHFUSS,R: DABROWIAK,JC: CATINO,JJ: MUSIAL,ST: BROOKSHIRE,KW: DOYLE,TW:. (1989). ESPERAMICINS, A CLASS OF POTENT ANTITUMOR ANTIBIOTICS: MECHANISM OF ACTION.. 86(1)

Citation Details

Title	ESPERAMICINS, A CLASS OF POTENT ANTITUMOR ANTIBIOTICS: MECHANISM OF ACTION.
Authors	LONG,BH: GOLIK,J: FORENZA,S: WARD,B: REHFUSS,R: DABROWIAK,JC: CATINO,JJ: MUSIAL,ST: BROOKSHIRE,KW: DOYLE,TW:
Year	1989
Volume	86
Issue	1

Summary

Year: 1989

Journal: Unknown

Organisms and Their Experiments (6)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN A-1	STRONG ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN A-1	STRONG ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN A-1	STRONG ACTIVITY
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN A-1	STRONG ACTIVITY
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN A-1	STRONG ACTIVITY
6	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN A-1	STRONG ACTIVITY
7	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN A-1	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN C	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN C	STRONG ACTIVITY
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN C	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN C	ACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN C	ACTIVE
6	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN C	ACTIVE
7	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN C	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN D	WEAK ACTIVITY
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN D	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN D	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN D	INACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN D	WEAK ACTIVITY
6	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN D	ACTIVE
7	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN D	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN E	INACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN E	INACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN E	INACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN E	INACTIVE
5	METASTASIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN E	INACTIVE
6	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN E	WEAK ACTIVITY
7	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN E	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN X	INACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN X	INACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN X	INACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN X	INACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN X	INACTIVE
6	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN X	ACTIVE
7	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN X	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN Z	INACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN Z	INACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN Z	INACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN Z	INACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	ESPERAMICIN Z	INACTIVE
6	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN Z	WEAK ACTIVITY
7	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	ESPERAMICIN Z	INACTIVE

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