Citation 183255

WATANABE,K: ARAI,M: NARIMATSU,S: YAMAMOTO,I: YOSHIMURA,H:. (1987). IN VIVO EFFECTS OF TETRAHYDROCANNABINOLS AND THEIR EIGHT MONOOXYGENATED METABOLITES ON THE HEPATIC MILCROSOMAL DRUG-METABOLIZING ENZYME SYSTEMS OF MICE.. 10(10)

Citation Details

Title	IN VIVO EFFECTS OF TETRAHYDROCANNABINOLS AND THEIR EIGHT MONOOXYGENATED METABOLITES ON THE HEPATIC MILCROSOMAL DRUG-METABOLIZING ENZYME SYSTEMS OF MICE.
Authors	WATANABE,K: ARAI,M: NARIMATSU,S: YAMAMOTO,I: YOSHIMURA,H:
Year	1987
Volume	10
Issue	10

Summary

Year: 1987

Journal: Unknown

Organisms and Their Experiments (6)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME P450 INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO:	INACTIVE
2	CYTOCHROME B-5 INCREASE	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO:	INACTIVE
3	NADPH-CYTOCHROME C REDUCTASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO:	INACTIVE
4	PARANITROANISOLE-O-DEMETHYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO:	INACTIVE
5	ANILINE HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME P450 INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-ALPHA-HYDROXY:	INACTIVE
2	CYTOCHROME B-5 INCREASE	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-ALPHA-HYDROXY:	INACTIVE
3	NADPH-CYTOCHROME C REDUCTASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-ALPHA-HYDROXY:	ACTIVE
4	PARANITROANISOLE-O-DEMETHYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-ALPHA-HYDROXY:	ACTIVE
5	ANILINE HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-ALPHA-HYDROXY:	INACTIVE
6	UDP-GLUCURONYL TRANSFERASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-ALPHA-HYDROXY:	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME P450 INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-BETA-HYDROXY:	ACTIVE
2	CYTOCHROME B-5 INCREASE	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-BETA-HYDROXY:	ACTIVE
3	NADPH-CYTOCHROME C REDUCTASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-BETA-HYDROXY:	ACTIVE
4	PARANITROANISOLE-O-DEMETHYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-BETA-HYDROXY:	ACTIVE
5	ANILINE HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-BETA-HYDROXY:	INACTIVE
6	UDP-GLUCURONYL TRANSFERASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-8-TETRAHYDRO: 7-BETA-HYDROXY:	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME P450 INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO:	INACTIVE
2	CYTOCHROME B-5 INCREASE	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO:	INACTIVE
3	NADPH-CYTOCHROME C REDUCTASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO:	ACTIVE
4	PARANITROANISOLE-O-DEMETHYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO:	INACTIVE
5	ANILINE HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO:	INACTIVE
6	UDP-GLUCURONYL TRANSFERASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO:	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME P450 INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-ALPHA-HYDROXY:	INACTIVE
2	CYTOCHROME B-5 INCREASE	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-ALPHA-HYDROXY:	INACTIVE
3	NADPH-CYTOCHROME C REDUCTASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-ALPHA-HYDROXY:	ACTIVE
4	PARANITROANISOLE-O-DEMETHYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-ALPHA-HYDROXY:	INACTIVE
5	ANILINE HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-ALPHA-HYDROXY:	INACTIVE
6	UDP-GLUCURONYL TRANSFERASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-ALPHA-HYDROXY:	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOCHROME P450 INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-BETA-HYDROXY:	INACTIVE
2	CYTOCHROME B-5 INCREASE	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-BETA-HYDROXY:	INACTIVE
3	NADPH-CYTOCHROME C REDUCTASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-BETA-HYDROXY:	INACTIVE
4	PARANITROANISOLE-O-DEMETHYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-BETA-HYDROXY:	INACTIVE
5	ANILINE HYDROXYLASE INDUCTION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-BETA-HYDROXY:	INACTIVE
6	UDP-GLUCURONYL TRANSFERASE STIMULATION	PHARMACOLOGY OF COMPOUND - IN VIVO	CANNABINOL,DELTA-9-TETRAHYDRO: 8-BETA-HYDROXY:	INACTIVE

Citation 183255

Citation Details

Summary

Organisms and Their Experiments (6)

Unknown organism

Unknown organism

Unknown organism

Unknown organism

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Unknown organism

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