CHEMICAL MODIFICATION OF ANSAMITOCINS. III. SYNTHESIS AND BIOLOGICAL EFFECTS OF 3-ACYL ESTERS OF MAYTANSINOL.

Title	CHEMICAL MODIFICATION OF ANSAMITOCINS. III. SYNTHESIS AND BIOLOGICAL EFFECTS OF 3-ACYL ESTERS OF MAYTANSINOL.
Authors	KAWAI,A: AKIMOTO,H: KOZAI,Y: OOTSU,K: TANIDA,S: HASHIMOTO,N: NOMURA,H:
Year	1984
Volume	32
Issue	9

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINE	ACTIVE
2	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINE	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-N-BENZOYL-N-METHYL-L-ALANINATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-N-BENZOYL-N-METHYL-L-ALANINATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-N-BENZOYL-N-METHYL-L-ALANINATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-N-PHENOXY-ACETYL-N-METHYL-L-ALANINATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-N-PHENOXY-ACETYL-N-METHYL-L-ALANINATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-N-PHENOXY-ACETYL-N-METHYL-L-ALANINATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-N-ACETYL-N-BENZYL-L-ALANINATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-N-ACETYL-N-BENZYL-L-ALANINATE	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-N-ACETYL-N-BENZYL-L-ALANINATE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-N-ACETYL-N-METHYL-L-LEUCINATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-N-ACETYL-N-METHYL-L-LEUCINATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-N-ACETYL-N-METHYL-L-LEUCINATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-N-ACETYL-N-METHYL-L-LEUCINATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-N-ACETYL-N-METHYL-L-PHENYL-ALANINATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-N-ACETYL-N-METHYL-L-PHENYL-ALANINATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-N-ACETYL-N-METHYL-L-PHENYL-ALANINATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-N-ACETYL-N-METHYL-L-PHENYL-ALANINATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-N-ACETYL-L-PROLINATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-N-ACETYL-L-PROLINATE	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-N-ACETYL-L-PROLINATE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTED	MAYTANSINOL-3-BUTYRATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-BUTYRATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-BUTYRATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-VALERATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-VALERATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-VALERATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-VALERATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-HEXANOATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-HEXANOATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-HEXANOATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-HEXANOATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-HEPTANOATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-HEPTANOATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-HEPTANOATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-HEPTANOATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-OCTANOATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-OCTANOATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-OCTANOATE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-DECANOATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-DECANOATE	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-DECANOATE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-TRIDECANOATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-TRIDECANOATE	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-TRIDECANOATE	INACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-PALMITATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-PALMITATE	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-PALMITATE	INACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-PALMITATE	None

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-CYCLOPROPANECARBOXYLATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-CYCLOPROPANECARBOXYLATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-CYCLOPROPANECARBOXYLATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-CYCLOPROPANECARBOXYLATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-CYCLOBUTANECARBOXYLATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-CYCLOBUTANECARBOXYLATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-CYCLOBUTANECARBOXYLATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-CYCLOBUTANECARBOXYLATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-CYCLOHEXANECARBOXYLATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-CYCLOHEXANECARBOXYLATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-CYCLOHEXANECARBOXYLATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-CYCLOHEXANECARBOXYLATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-BENZOATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-BENZOATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-BENZOATE	INACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-BENZOATE	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-PHENYL-ACETATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-PHENYL-ACETATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-PHENYL-ACETATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-PHENYL-ACETATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-(3-PHENYL-PROPIONATE)	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-(3-PHENYL-PROPIONATE)	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-(3-PHENYL-PROPIONATE)	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-PHENOXY-ACETATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-PHENOXY-ACETATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-PHENOXY-ACETATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-PHENOXY-ACETATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-(2-FURYL-CARBOXYLATE)	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-(2-FURYL-CARBOXYLATE)	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-(2-FURYL-CARBOXYLATE)	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-(2-FURYL-CARBOXYLATE)	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-(2-PYRIDINE-CARBOXYLATE)	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-(2-PYRIDINE-CARBOXYLATE)	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-(2-PYRIDINE-CARBOXYLATE)	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-(2-PYRIDINE-CARBOXYLATE)	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-(3-PYRIDINE-CARBOXYLATE)	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-(3-PYRIDINE-CARBOXYLATE)	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-(3-PYRIDINE-CARBOXYLATE)	INACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-(3-PYRIDINE-CARBOXYLATE)	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-(4-PYRIDINE-CARBOXYLATE)	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-(4-PYRIDINE-CARBOXYLATE)	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-(4-PYRIDINE-CARBOXYLATE)	INACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-(4-PYRIDINE-CARBOXYLATE)	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-PHENYL-CARBAMATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-PHENYL-CARBAMATE	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-PHENYL-CARBAMATE	INACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-PHENYL-CARBAMATE	WEAK ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-ISO-PROPYL-CARBONATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-ISO-PROPYL-CARBONATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-ISO-PROPYL-CARBONATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-ISO-PROPYL-CARBONATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-L-PHENYL-GLYCINATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-L-PHENYL-GLYCINATE	INACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-L-PHENYL-GLYCINATE	INACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-L-PHENYL-GLYCINATE	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-L-PHENYL-GLYCINATE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	COMPLETE SYNTHESIS REPORTEDMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FOR	MAYTANSINOL-3-L-MANDELATE	None
2	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	MAYTANSINOL-3-L-MANDELATE	ACTIVE
3	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	MAYTANSINOL-3-L-MANDELATE	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINOL-3-L-MANDELATE	ACTIVE

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Organisms and Their Experiments (30)

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