Citation 48773

KUPCHAN,SM: KOMODA,Y: COURT,WA: THOMAS,GJ: SMITH,RM: KARIM,A: GILMORE,CJ: HALTIWANGER,RC: BRYAN,RF:. (1972). TUMOR INHIBITORS. LXXIII. MAYTANSINE, A NOVEL ANTILEUKEMIC ANSA MACROLIDE FROM MAYTENUS OVATUS.. 94()

Citation Details

Title	TUMOR INHIBITORS. LXXIII. MAYTANSINE, A NOVEL ANTILEUKEMIC ANSA MACROLIDE FROM MAYTENUS OVATUS.
Authors	KUPCHAN,SM: KOMODA,Y: COURT,WA: THOMAS,GJ: SMITH,RM: KARIM,A: GILMORE,CJ: HALTIWANGER,RC: BRYAN,RF:
Year	1972
Volume	94
Issue

Summary

Year: 1972

Journal: Unknown

Organisms and Their Experiments (8)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE

Maytenus serrata (CELASTRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDX-RAY CHRYSTALLOGRAPHIC STUDIESQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTUREYIELD IS LESS THAN 50 MGM	MAYTANSINE	None
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	MAYTANSINE	ACTIVE

Maytenus serrata (CELASTRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE

Maytenus serrata (CELASTRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE

Maytenus serrata (CELASTRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE

Maytenus serrata (CELASTRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE

Maytenus serrata (CELASTRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE

Maytenus serrata (CELASTRACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
2	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
3	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
4	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE
6	ANTITUMOR ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	None	ACTIVE

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