Citation 52309

FUJII,K: JAFFE,H: BISHOP,Y: ARNOLD,E: MACKINTOSH,D: EPSTEIN,SS:. (1970). STRUCTURE-ACTIVITY RELATIONS FOR METHYLENEDIOXYPHENYL AND RELATED COMPOUNDS ON HEPATIC MICROSOMAL ENZYME FUNCTION, AS MEASURED BY PROLONGATION OF HEXOBARBITAL NARCOSIS AND ZOXAZOLAMINE PARALYSIS IN MICE.. 16()

Citation Details

Title	STRUCTURE-ACTIVITY RELATIONS FOR METHYLENEDIOXYPHENYL AND RELATED COMPOUNDS ON HEPATIC MICROSOMAL ENZYME FUNCTION, AS MEASURED BY PROLONGATION OF HEXOBARBITAL NARCOSIS AND ZOXAZOLAMINE PARALYSIS IN MICE.
Authors	FUJII,K: JAFFE,H: BISHOP,Y: ARNOLD,E: MACKINTOSH,D: EPSTEIN,SS:
Year	1970
Volume	16
Issue

Summary

Year: 1970

Journal: Unknown

Organisms and Their Experiments (20)

Sassafras albidum (LAURACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	SAFROLE,DIHYDRO:	ACTIVE
2	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	SAFROLE,DIHYDRO:	.

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	SAFROLE,ISO:	ACTIVE
2	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	SAFROLE,ISO:	.

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	PODOPHYLLOTOXIN	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PODOPHYLLOTOXIN	ACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	GUAIARETIC ACID,NOR-DIHYDRO:	INACTIVE
2	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	GUAIARETIC ACID,NOR-DIHYDRO:	.

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	EMETINE,(-):	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	EMETINE,(-):	STRONG ACTIVITY

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	EUGENOL METHYL ETHER	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	EUGENOL METHYL ETHER	ACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	EUGENOL,ISO: METHYL ETHER	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	EUGENOL,ISO: METHYL ETHER	ACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	VERATRIC ACID	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	VERATRIC ACID	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	VERATRALDEHYDE	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	VERATRALDEHYDE	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	CONIDENDRIN,ALPHA:	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	CONIDENDRIN,ALPHA:	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	EUGENOL	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	EUGENOL	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	EUGENOL,ISO:	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	EUGENOL,ISO:	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	FERULIC ACID	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	FERULIC ACID	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	CONIFENDROL,BETA:	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	CONIFENDROL,BETA:	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	PROTOCATECHUIC ACID	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PROTOCATECHUIC ACID	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	SESAMIN	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	SESAMIN	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	APIOL	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	APIOL	INACTIVE

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	SESAMOL	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	SESAMOL	WEAK ACTIVITY

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TOXICITY ASSESSMENT(QUANTITATIVE)	PHARMACOLOGY OF COMPOUND - IN VIVO	PIPERINE	.
2	MICROSOMAL METABOLIZING SYSTEM INHIBITION	PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	PIPERINE	ACTIVE

Citation 52309

Citation Details

Summary

Organisms and Their Experiments (20)

Query 1