Citation 64724

TAKAHASHI,I: SAITOH,Y: YOSHIDA,M: SANO,H: NAKANO,H: MORIMOTO,M: TAMAOKI,T:. (1989). UCN-01 AND UCN-02, NEW SELECTIVE INHIBITORS OF PROTEIN KINASE C II. PURIFICATION, PHYSICO-CHEMICAL PROPERTIES, STRUCTURAL DETERMINATION AND BIOLOGICAL ACTIVIES.. 42(4)

Citation Details

Title	UCN-01 AND UCN-02, NEW SELECTIVE INHIBITORS OF PROTEIN KINASE C II. PURIFICATION, PHYSICO-CHEMICAL PROPERTIES, STRUCTURAL DETERMINATION AND BIOLOGICAL ACTIVIES.
Authors	TAKAHASHI,I: SAITOH,Y: YOSHIDA,M: SANO,H: NAKANO,H: MORIMOTO,M: TAMAOKI,T:
Year	1989
Volume	42
Issue	4

Summary

Year: 1989

Journal: Unknown

Organisms and Their Experiments (1)

Streptomyces species (STREPTOMYCETACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	UV SPECTRUM GIVEN FORPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	STREPTOMYCES ANTIBIOTIC UCN-01	None
2	PROTEIN KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STREPTOMYCES ANTIBIOTIC UCN-01	ACTIVE
3	PROTEIN KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STREPTOMYCES ANTIBIOTIC UCN-01	ACTIVE
4	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
5	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
6	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
7	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
8	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
9	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
10	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
11	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
12	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
13	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
14	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STREPTOMYCES ANTIBIOTIC UCN-01	ACTIVE
15	TOXICITY ASSESSMENT(QUANTITATIVE)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVO	STREPTOMYCES ANTIBIOTIC UCN-01	.
16	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	STREPTOMYCES ANTIBIOTIC UCN-01	INACTIVE
17	Not specified	UV SPECTRUM GIVEN FORPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	STREPTOMYCES ANTIBIOTIC UCN-02	None
18	RESPIRATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STREPTOMYCES ANTIBIOTIC UCN-02	ACTIVE
19	RESPIRATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STREPTOMYCES ANTIBIOTIC UCN-02	ACTIVE
20	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
21	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
22	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
23	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
24	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
25	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
26	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
27	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
28	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
29	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
30	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STREPTOMYCES ANTIBIOTIC UCN-02	ACTIVE
31	TOXIC EFFECT(GENERAL)	TOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VIVO	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
32	DNA SCISSION EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	STREPTOMYCES ANTIBIOTIC UCN-02	INACTIVE
33	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	STAUROSPORINE	None
34	RESPIRATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STAUROSPORINE	ACTIVE
35	RESPIRATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STAUROSPORINE	ACTIVE

Citation 64724

Citation Details

Summary

Organisms and Their Experiments (1)

Streptomyces species (STREPTOMYCETACEAE)

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