Citation 68704

KAWASHIMA,A: NAKAMURA,Y: OHTA,Y: AKAMA,T: YAMAGISHI,M: HANADA,K:. (1992). NEW CHOLESTEROL BIOSYNTHESIS INHIBITORS MC-031 (O-DEMETHYLCHLOROTHRICIN), -032 (O-DEMETHYLHYDROXYCHLOROTHRICIN), -033 AND -034.. 45(2)

Citation Details

Title	NEW CHOLESTEROL BIOSYNTHESIS INHIBITORS MC-031 (O-DEMETHYLCHLOROTHRICIN), -032 (O-DEMETHYLHYDROXYCHLOROTHRICIN), -033 AND -034.
Authors	KAWASHIMA,A: NAKAMURA,Y: OHTA,Y: AKAMA,T: YAMAGISHI,M: HANADA,K:
Year	1992
Volume	45
Issue	2

Summary

Year: 1992

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	PMR SPECTRUM REPORTEDCMR SPECTRUM REPORTED	CHLOROTHRICIN	None
2	CHOLESTEROL SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHLOROTHRICIN	ACTIVE
3	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	CHLOROTHRICIN	EQUIVOCAL
4	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	CHLOROTHRICIN	ACTIVE
5	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	CHLOROTHRICIN	ACTIVE
6	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	CHLOROTHRICIN	INACTIVE
7	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	CHLOROTHRICIN	INACTIVE
8	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	CHLOROTHRICIN	INACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CHLOROTHRICIN	ACTIVE

Streptomyces species (STREPTOMYCETACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	UV SPECTRUM GIVEN FORPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CHLOROTHRICIN,O-DEMETHYL:	None
2	Not specified	UV SPECTRUM GIVEN FORPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CHLOROTHRICIN,O-DEMETHYL: HYDROXY:	None
3	Not specified	UV SPECTRUM GIVEN FORPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	STREPTOMYCES ANTIBIOTIC MC-033	None
4	CHOLESTEROL SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STREPTOMYCES ANTIBIOTIC MC-033	ACTIVE
5	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-033	EQUIVOCAL
6	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-033	ACTIVE
7	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-033	ACTIVE
8	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-033	INACTIVE
9	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-033	INACTIVE
10	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-033	INACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STREPTOMYCES ANTIBIOTIC MC-033	ACTIVE
12	Not specified	UV SPECTRUM GIVEN FORPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	STREPTOMYCES ANTIBIOTIC MC-034	None
13	CHOLESTEROL SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STREPTOMYCES ANTIBIOTIC MC-034	ACTIVE
14	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-034	INACTIVE
15	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-034	ACTIVE
16	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-034	EQUIVOCAL
17	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-034	INACTIVE
18	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-034	INACTIVE
19	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	STREPTOMYCES ANTIBIOTIC MC-034	INACTIVE
20	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STREPTOMYCES ANTIBIOTIC MC-034	ACTIVE