Citation 69170

GRABLEY,S: GRANZER,E: HOTTER,K: LUDWIG,D: MAYER,M: THIERICKE,R: TILL: WINK,J: AG,H:. (1992). SECONDARY METABOLITES BY CHEMICAL SCREENING. 8. DECARESTRICTINES, A NEW FAMILY OF INHIBITORS OF CHOLESTEROL BIOSYNTHESIS FROM PENICILLIUM. I. STRAIN DESCRIPTION, FERMENTATION, ISOLATION AND PROPERTIES.. 45(1)

Citation Details

Title	SECONDARY METABOLITES BY CHEMICAL SCREENING. 8. DECARESTRICTINES, A NEW FAMILY OF INHIBITORS OF CHOLESTEROL BIOSYNTHESIS FROM PENICILLIUM. I. STRAIN DESCRIPTION, FERMENTATION, ISOLATION AND PROPERTIES.
Authors	GRABLEY,S: GRANZER,E: HOTTER,K: LUDWIG,D: MAYER,M: THIERICKE,R: TILL: WINK,J: AG,H:
Year	1992
Volume	45
Issue	1

Summary

Year: 1992

Journal: Unknown

Organisms and Their Experiments (2)

Penicillium simplicissimum (HYPHOMYCETES)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	QUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	DECARESTRICTINE A	None
2	CHOLESTEROL SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	DECARESTRICTINE A	ACTIVE
3	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE A	INACTIVE
4	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE A	INACTIVE
5	ANTIVIRAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE A	INACTIVE
6	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE A	INACTIVE
7	Not specified	QUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	DECARESTRICTINE B	None
8	CHOLESTEROL SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	DECARESTRICTINE B	ACTIVE
9	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE B	INACTIVE
10	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE B	INACTIVE
11	ANTIVIRAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE B	INACTIVE
12	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE B	INACTIVE
13	Not specified	QUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	DECARESTRICTINE C	None
14	CHOLESTEROL SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	DECARESTRICTINE C	ACTIVE
15	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE C	INACTIVE
16	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE C	INACTIVE
17	ANTIVIRAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE C	INACTIVE
18	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE C	INACTIVE
19	Not specified	QUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	DECARESTRICTINE D	None
20	CHOLESTEROL SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	DECARESTRICTINE D	ACTIVE
21	HYPOLIPEMIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVO	DECARESTRICTINE D	ACTIVE
22	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE D	INACTIVE
23	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE D	INACTIVE
24	ANTIVIRAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE D	INACTIVE
25	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	DECARESTRICTINE D	INACTIVE

Penicillium corylophilum (HYPHOMYCETES)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OFMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATA	AGROCLAVINE I,EPOXY:	None