Citation 70026

YOSHIMOTO,A: FUJII,S: JOHDO,O: KUBO,K: NISHIDA,H: OKAMOTO,R: TAKEUCHI,T:. (1993). ANTHRACYCLINE METABOLITES FROM BAUMYCIN-PRODUCING STREPTOMYCES SP.D788. II. NEW ANTHRACYCLINE METABOLITES PRODUCED BY A BLOCKED MUTANT STRAIN RPM-5.. 46(1)

Citation Details

Title	ANTHRACYCLINE METABOLITES FROM BAUMYCIN-PRODUCING STREPTOMYCES SP.D788. II. NEW ANTHRACYCLINE METABOLITES PRODUCED BY A BLOCKED MUTANT STRAIN RPM-5.
Authors	YOSHIMOTO,A: FUJII,S: JOHDO,O: KUBO,K: NISHIDA,H: OKAMOTO,R: TAKEUCHI,T:
Year	1993
Volume	46
Issue	1

Summary

Year: 1993

Journal: Unknown

Organisms and Their Experiments (1)

Streptomyces species (STREPTOMYCETACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OFPMR SPECTRUM REPORTEDQUANTITATIVE DATA	CARMINOMYCIN,10-CARBOXY-13-DEOXO:	None
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,10-CARBOXY-13-DEOXO:	STRONG ACTIVITY
3	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,10-CARBOXY-13-DEOXO:	INACTIVE
4	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,10-CARBOXY-13-DEOXO:	INACTIVE
5	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,10-CARBOXY-13-DEOXO:	INACTIVE
6	Not specified	ISOLATION AND IDENTIFICATION OFPMR SPECTRUM REPORTEDQUANTITATIVE DATA	CARMINOMYCIN,9-10-ANHYDRO-13-DEOXO:	None
7	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDHPLC DATA REPORTEDTLC DATA REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CARMINOMYCIN,10-METHOXY-CARBONYL-13-DEOXO:	None
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,9-10-ANHYDRO-13-DEOXO:	ACTIVE
9	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,9-10-ANHYDRO-13-DEOXO:	ACTIVE
10	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,9-10-ANHYDRO-13-DEOXO:	ACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,10-METHOXY-CARBONYL-13-DEOXO:	ACTIVE
12	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,10-METHOXY-CARBONYL-13-DEOXO:	ACTIVE
13	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,10-METHOXY-CARBONYL-13-DEOXO:	ACTIVE
14	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,9-10-ANHYDRO-13-DEOXO:CARMINOMYCIN,10-METHOXY-CARBONYL-13-DEOXO:	INACTIVE
15	Not specified	ISOLATION AND IDENTIFICATION OFPMR SPECTRUM REPORTEDQUANTITATIVE DATA	OXAUNOMYCIN	None
16	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDHPLC DATA REPORTEDTLC DATA REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CARMINOMYCIN,9-10-ANHYDRO-13-HYDRO:	None
17	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,9-10-ANHYDRO-13-HYDRO:	ACTIVE
18	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,9-10-ANHYDRO-13-HYDRO:	ACTIVE
19	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	OXAUNOMYCINCARMINOMYCIN,9-10-ANHYDRO-13-HYDRO:	INACTIVE
20	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	OXAUNOMYCIN	STRONG ACTIVITY
21	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OXAUNOMYCIN	ACTIVE
22	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OXAUNOMYCIN	ACTIVE
23	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDHPLC DATA REPORTEDTLC DATA REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	FEUDOMYCIN B,10-METHOXY-CARBONYL-4-O-DEMETHYL:	None
24	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDHPLC DATA REPORTEDTLC DATA REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	FEUDOMYCIN C,10-CARBOXY-4-O-DEMETHYL:	None
25	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	FEUDOMYCIN B,10-METHOXY-CARBONYL-4-O-DEMETHYL:	ACTIVE
26	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FEUDOMYCIN B,10-METHOXY-CARBONYL-4-O-DEMETHYL:	ACTIVE
27	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FEUDOMYCIN B,10-METHOXY-CARBONYL-4-O-DEMETHYL:	ACTIVE
28	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	FEUDOMYCIN B,10-METHOXY-CARBONYL-4-O-DEMETHYL:FEUDOMYCIN C,10-CARBOXY-4-O-DEMETHYL:	INACTIVE
29	Not specified	ISOLATION AND IDENTIFICATION OFPMR SPECTRUM REPORTEDQUANTITATIVE DATA	CARMINOMYCIN,13-DEOXO:	None
30	Not specified	ISOLATION AND IDENTIFICATION OFPMR SPECTRUM REPORTEDQUANTITATIVE DATA	CARMINOMYCIN,13-DIHYDRO:	None
31	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,13-DEOXO:	STRONG ACTIVITY
32	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,13-DEOXO:	ACTIVE
33	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,13-DEOXO:	ACTIVE
34	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,13-DIHYDRO:	ACTIVE
35	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,13-DIHYDRO:	ACTIVE
36	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,13-DIHYDRO:	ACTIVE
37	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CARMINOMYCIN,13-DEOXO:CARMINOMYCIN,13-DIHYDRO:	INACTIVE
38	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDHPLC DATA REPORTEDTLC DATA REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	FEUDOMYCIN C,10-METHOXY-CARBONYL-4-O-DEMETHYL:	None
39	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	FEUDOMYCIN C,10-METHOXY-CARBONYL-4-O-DEMETHYL:	ACTIVE
40	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FEUDOMYCIN C,10-METHOXY-CARBONYL-4-O-DEMETHYL:	INACTIVE
41	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FEUDOMYCIN C,10-METHOXY-CARBONYL-4-O-DEMETHYL:	INACTIVE
42	ANTITUMOR ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE	FEUDOMYCIN C,10-METHOXY-CARBONYL-4-O-DEMETHYL:	INACTIVE
43	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CARMINOMYCIN,9-10-ANHYDRO-13-HYDRO:	ACTIVE
44	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	FEUDOMYCIN C,10-CARBOXY-4-O-DEMETHYL:	ACTIVE
45	DNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FEUDOMYCIN C,10-CARBOXY-4-O-DEMETHYL:	INACTIVE
46	RNA SYNTHESIS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	FEUDOMYCIN C,10-CARBOXY-4-O-DEMETHYL:	INACTIVE

Citation 70026

Citation Details

Summary

Organisms and Their Experiments (1)

Streptomyces species (STREPTOMYCETACEAE)

Show SPARQL Queries (1)

Query 1