Citation 71560

PATIL,AD: FREYER,AJ: EGGLESTON,DS: HALTIWANGER,RC: BEAN,MF: TAYLOR,PB: CARANFA,MJ: BREEN,AL: BARTUS,HR: JOHNSON,RK: HERTZBERG,RP: WESTLEY,JW:. (1993). THE INOPHYLLUMS, NOVEL INHIBITORS OF HIV-1 REVERSE TRANSCRIPTASE ISOLATED FROM THE MALAYSIAN TREE, CALOPHYLLUM INOPHYLLUM LINN.. 36(26)

Citation Details

Title	THE INOPHYLLUMS, NOVEL INHIBITORS OF HIV-1 REVERSE TRANSCRIPTASE ISOLATED FROM THE MALAYSIAN TREE, CALOPHYLLUM INOPHYLLUM LINN.
Authors	PATIL,AD: FREYER,AJ: EGGLESTON,DS: HALTIWANGER,RC: BEAN,MF: TAYLOR,PB: CARANFA,MJ: BREEN,AL: BARTUS,HR: JOHNSON,RK: HERTZBERG,RP: WESTLEY,JW:
Year	1993
Volume	36
Issue	26

Summary

Year: 1993

Journal: Unknown

Organisms and Their Experiments (3)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	INOPHYLLUM P ACETATE*	ACTIVE
2	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	INOPHYLLUM B ACETATE*	ACTIVE
3	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	INOPHYLLUM P,11-12-ANHYDRO:*	ACTIVE

Calophyllum inophyllum (CLUSIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FORISOLATION AND IDENTIFICATION OFCMR SPECTRUM REPORTEDQUANTITATIVE DATA	CALOPHYLLOLIDE	None
2	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF EXTRACT - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	None	ACTIVE
3	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CALOPHYLLOLIDE	INACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CALOPHYLLOLIDE	ACTIVE
5	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	INOPHYLLUM G-1	None
6	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	INOPHYLLUM G-1	INACTIVE
7	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	INOPHYLLUM P	None
8	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	INOPHYLLUM P	ACTIVE
9	ANTIVIRAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	INOPHYLLUM P	ACTIVE
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	INOPHYLLUM P	WEAK ACTIVITY
11	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	INOPHYLLUM G-2	None
12	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	INOPHYLLUM G-2	ACTIVE
13	Not specified	ISOLATION AND IDENTIFICATION OFCMR SPECTRUM REPORTEDQUANTITATIVE DATA	INOPHYLLUM A	None
14	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	INOPHYLLUM A	ACTIVE
15	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	INOPHYLLUM A	WEAK ACTIVITY
16	Not specified	ISOLATION AND IDENTIFICATION OFCMR SPECTRUM REPORTEDQUANTITATIVE DATA	INOPHYLLUM B	None
17	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE	INOPHYLLUM B	ACTIVE
18	ANTIVIRAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	INOPHYLLUM B	ACTIVE
19	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTICANCER AND/OR CYTOTOXICITY MARKER CODE	INOPHYLLUM B	WEAK ACTIVITY
20	Not specified	ISOLATION AND IDENTIFICATION OFCMR SPECTRUM REPORTEDQUANTITATIVE DATA	INOPHYLLUM C	None
21	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	INOPHYLLUM C	ACTIVE
22	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	INOPHYLLUM C	ACTIVE
23	Not specified	ISOLATION AND IDENTIFICATION OFCMR SPECTRUM REPORTEDQUANTITATIVE DATA	INOPHYLLUM D	None
24	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	INOPHYLLUM D	ACTIVE
25	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	INOPHYLLUM D	ACTIVE
26	Not specified	ISOLATION AND IDENTIFICATION OFCMR SPECTRUM REPORTEDQUANTITATIVE DATA	INOPHYLLUM E	None
27	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	INOPHYLLUM E	WEAK ACTIVITY
28	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	INOPHYLLUM E	ACTIVE
29	Not specified	ISOLATION AND IDENTIFICATION OFPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATA	CALOPHYLLIC ACID	None
30	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CALOPHYLLIC ACID	INACTIVE
31	Not specified	ISOLATION AND IDENTIFICATION OFPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATA	CALOPHYLLIC ACID,ISO:	None
32	REVERSE TRANSCRIPTASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CALOPHYLLIC ACID,ISO:	INACTIVE

Achatina fulica (ACHATINIDAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OFX-RAY CHRYSTALLOGRAPHIC STUDIESQUANTITATIVE DATA	INOPHYLLUM A	None
2	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	INOPHYLLUM B	None
3	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	INOPHYLLUM C	None
4	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	INOPHYLLUM D	None
5	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	INOPHYLLUM E	None
6	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	CALOPHYLLOLIDE	None