Citation 71562

WICKRAMARATNE,DBM: PENGSUSARP,T: MAR,W: CHAI,HB: CHAGWEDERA,TE: BEECHER,CWW: FARNSWORTH,NR: KINGHORN,AD: PEZZUTO,JM: CORDELL,GA:. (1993). NOVEL ANTIMITOTIC DIBENZOCYCLO-OCTADIENE LIGNAN CONSTITUENTS OF THE STEM BARK OF STEGANOTAENIA ARALIACEA.. 56(12)

Citation Details

Title	NOVEL ANTIMITOTIC DIBENZOCYCLO-OCTADIENE LIGNAN CONSTITUENTS OF THE STEM BARK OF STEGANOTAENIA ARALIACEA.
Authors	WICKRAMARATNE,DBM: PENGSUSARP,T: MAR,W: CHAI,HB: CHAGWEDERA,TE: BEECHER,CWW: FARNSWORTH,NR: KINGHORN,AD: PEZZUTO,JM: CORDELL,GA:
Year	1993
Volume	56
Issue	12

Summary

Year: 1993

Journal: Unknown

Organisms and Their Experiments (3)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TUBULIN POLYMERIZATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	COLCHICINE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TUBULIN POLYMERIZATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANONE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	ACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	ACTIVE
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	ACTIVE
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	WEAK ACTIVITY
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	ACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	ACTIVE
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	INACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	INACTIVE
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANONE	INACTIVE

Steganotaenia araliacea (APIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	LYMPHOCYTE PROLIFERATION STIMULATION	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATACD SPECTRUM REPORTED FOR	STEGANANGIN	None
4	TUBULIN POLYMERIZATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANANGIN	WEAK ACTIVITY
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	INACTIVE
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
13	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
14	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	INACTIVE
15	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN	ACTIVE
16	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURECD SPECTRUM REPORTED FOR	STEGANANGIN,EPI:	None
17	TUBULIN POLYMERIZATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANANGIN,EPI:	WEAK ACTIVITY
18	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	INACTIVE
19	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	ACTIVE
20	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	INACTIVE
21	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	WEAK ACTIVITY
22	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	WEAK ACTIVITY
23	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	ACTIVE
24	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	INACTIVE
25	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	WEAK ACTIVITY
26	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	INACTIVE
27	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	INACTIVE
28	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANANGIN,EPI:	WEAK ACTIVITY
29	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	STEGANACIN	None
30	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANACIN	ACTIVE
31	TUBULIN POLYMERIZATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANACIN	ACTIVE
32	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
33	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
34	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
35	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
36	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
37	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
38	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
39	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
40	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
41	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	ACTIVE
42	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANACIN	INACTIVE
43	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURECD SPECTRUM REPORTED FOR	STEGANOATE A	None
44	TUBULIN POLYMERIZATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANOATE A	WEAK ACTIVITY
45	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
46	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
47	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
48	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
49	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
50	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
51	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
52	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
53	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
54	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
55	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE A	INACTIVE
56	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURECD SPECTRUM REPORTED FOR	STEGANOATE B	None
57	TUBULIN POLYMERIZATION INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANOATE B	WEAK ACTIVITY
58	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	WEAK ACTIVITY
59	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	WEAK ACTIVITY
60	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	WEAK ACTIVITY
61	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	WEAK ACTIVITY
62	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	WEAK ACTIVITY
63	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	ACTIVE
64	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	INACTIVE
65	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	WEAK ACTIVITY
66	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	WEAK ACTIVITY
67	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	WEAK ACTIVITY
68	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOATE B	ACTIVE
69	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATACD SPECTRUM REPORTED FOR	STEGANOLIDE A	None
70	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANOLIDE A	ACTIVE
71	MICROTUBULE ASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	STEGANOLIDE A	INACTIVE
72	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	WEAK ACTIVITY
73	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	WEAK ACTIVITY
74	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	WEAK ACTIVITY
75	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	WEAK ACTIVITY
76	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	ACTIVE
77	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	ACTIVE
78	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	WEAK ACTIVITY
79	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	WEAK ACTIVITY
80	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	WEAK ACTIVITY
81	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	ACTIVE
82	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	STEGANOLIDE A	WEAK ACTIVITY

Citation 71562

Citation Details

Summary

Organisms and Their Experiments (3)

Unknown organism

Unknown organism

Steganotaenia araliacea (APIACEAE)

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