Citation 72476

GERWICK,WH: PROTEAU,PJ: NAGLE,DG: HAMEL,E: BLOKHIN,A: SLATE,DL:. (1994). STRUCTURE OF CURACIN A, A NOVEL ANTIMITOTIC, ANTIPROLIFERATIVE, AND BRINE SHRIMP TOXIC NATURAL PRODUCT FROM THE MARINE CYANOBACTERIUM LYNGBYA MAJUSCULA.. 59(6)

Citation Details

Title	STRUCTURE OF CURACIN A, A NOVEL ANTIMITOTIC, ANTIPROLIFERATIVE, AND BRINE SHRIMP TOXIC NATURAL PRODUCT FROM THE MARINE CYANOBACTERIUM LYNGBYA MAJUSCULA.
Authors	GERWICK,WH: PROTEAU,PJ: NAGLE,DG: HAMEL,E: BLOKHIN,A: SLATE,DL:
Year	1994
Volume	59
Issue	6

Summary

Year: 1994

Journal: Unknown

Organisms and Their Experiments (3)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	TUBULIN BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	MAYTANSINE	ACTIVE
2	TUBULIN BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	PODOPHYLLOTOXIN	STRONG ACTIVITY

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	ANTIMITOTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLCHICINE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE
3	ANTIMITOTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLCHICINE	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	COLCHICINE	ACTIVE

Lyngbya majuscula (OSCILLATORIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	PMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURECOMPOUND ISOLATED HAS UNUSUAL NAME	CURACIN A	None
2	ANTICRUSTACEAN ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	CURACIN A	STRONG ACTIVITY
3	ANTIPROLIFERATION ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CURACIN A	STRONG ACTIVITY
4	ANTICRUSTACEAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CURACIN A	STRONG ACTIVITY
5	TUBULIN BINDING INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CURACIN A	ACTIVE
6	ANTIMITOTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CURACIN A	STRONG ACTIVITY
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CURACIN A	STRONG ACTIVITY
8	ANTIMITOTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CURACIN A	ACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CURACIN A	STRONG ACTIVITY

Citation 72476

Citation Details

Summary

Organisms and Their Experiments (3)

Unknown organism

Unknown organism

Lyngbya majuscula (OSCILLATORIACEAE)

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