Citation 72553

KOBAYASHI,J: OGIWARA,A: HOSOYAMA,H: SHIGEMORI,H: YOSHIDA,N: SASAKI,T: LI,Y: IWASAKI,S: NAITO,M: TSURUO,T:. (1994). TAXUSPINES A - C, NEW TAXOIDS FROM JAPANESE NEW TAXUS CUSPIDATA INHIBITING DRUG TRANSPORT ACTIVITY OF P-GLYCOPROTEIN IN MULTIDRUG-RESISTANT CELLS.. 50(25)

Citation Details

Title	TAXUSPINES A - C, NEW TAXOIDS FROM JAPANESE NEW TAXUS CUSPIDATA INHIBITING DRUG TRANSPORT ACTIVITY OF P-GLYCOPROTEIN IN MULTIDRUG-RESISTANT CELLS.
Authors	KOBAYASHI,J: OGIWARA,A: HOSOYAMA,H: SHIGEMORI,H: YOSHIDA,N: SASAKI,T: LI,Y: IWASAKI,S: NAITO,M: TSURUO,T:
Year	1994
Volume	50
Issue	25

Summary

Year: 1994

Journal: Unknown

Organisms and Their Experiments (1)

Taxus cuspidata (TAXACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	TAXININE A	None
2	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE A	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE A	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE A	WEAK ACTIVITY
5	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE A	INACTIVE
6	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	TAXUSPINE A	None
7	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXUSPINE A	ACTIVE
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXUSPINE A	ACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXUSPINE A	WEAK ACTIVITY
10	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXUSPINE A	INACTIVE
11	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	TAXUSPINE B	None
12	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXUSPINE B	ACTIVE
13	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXUSPINE B	WEAK ACTIVITY
14	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXUSPINE B	INACTIVE
15	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXUSPINE B	ACTIVE
16	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	TAXUSPINE C	None
17	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXUSPINE C	ACTIVE
18	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXUSPINE C	ACTIVE
19	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXUSPINE C	INACTIVE
20	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXUSPINE C	INACTIVE
21	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	TAXININE	None
22	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE	ACTIVE
23	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE	INACTIVE
24	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE	INACTIVE
25	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE	INACTIVE
26	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	TAXININE B	None
27	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE B	ACTIVE
28	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE B	WEAK ACTIVITY
29	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE B	WEAK ACTIVITY
30	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE B	ACTIVE
31	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	TAXICIN I,O-CINNAMOYL: ACETATE	None
32	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXICIN I,O-CINNAMOYL: ACETATE	ACTIVE
33	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXICIN I,O-CINNAMOYL: ACETATE	ACTIVE
34	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXICIN I,O-CINNAMOYL: ACETATE	ACTIVE
35	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXICIN I,O-CINNAMOYL: ACETATE	INACTIVE
36	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	AUSTROSPICATINE,2-DEACETOXY:	None
37	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AUSTROSPICATINE,2-DEACETOXY:	ACTIVE
38	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AUSTROSPICATINE,2-DEACETOXY:	ACTIVE
39	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	AUSTROSPICATINE,2-DEACETOXY:	WEAK ACTIVITY
40	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	AUSTROSPICATINE,2-DEACETOXY:	INACTIVE
41	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	TAXININE E,2-DEACETOXY:	None
42	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE E,2-DEACETOXY:	ACTIVE
43	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE E,2-DEACETOXY:	ACTIVE
44	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE E,2-DEACETOXY:	ACTIVE
45	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE E,2-DEACETOXY:	INACTIVE
46	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	TAXININE J,2-DEACETOXY:	None
47	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE J,2-DEACETOXY:	ACTIVE
48	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE J,2-DEACETOXY:	ACTIVE
49	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXININE J,2-DEACETOXY:	WEAK ACTIVITY
50	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXININE J,2-DEACETOXY:	ACTIVE
51	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	TAXINE II	None
52	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXINE II	ACTIVE
53	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXINE II	WEAK ACTIVITY
54	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXINE II	EQUIVOCAL
55	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXINE II	INACTIVE
56	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	TAXOL	None
57	MULTIDRUG RESISTANCE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXOL	INACTIVE
58	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXOL	STRONG ACTIVITY
59	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	TAXOL	STRONG ACTIVITY
60	MICROTUBULE DISASSEMBLY INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	TAXOL	ACTIVE

Citation 72553

Citation Details

Summary

Organisms and Their Experiments (1)

Taxus cuspidata (TAXACEAE)

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