Citation 73497

MORRIS,SA: SCHWARTZ,RE: SESIN,DF: MASUREKAR,P: HALLADA,TC: SCHMATZ,DM: BARTIZAI,K: HENSENS,OD: ZINK,DL:. (1994). PNEUMOCANDIN D-0, A NEW ANTIFUNGAL AGENT AND POTENT INHIBITOR OF PNEUMOCYSTIS CARINII.. 47(7)

Citation Details

Title	PNEUMOCANDIN D-0, A NEW ANTIFUNGAL AGENT AND POTENT INHIBITOR OF PNEUMOCYSTIS CARINII.
Authors	MORRIS,SA: SCHWARTZ,RE: SESIN,DF: MASUREKAR,P: HALLADA,TC: SCHMATZ,DM: BARTIZAI,K: HENSENS,OD: ZINK,DL:
Year	1994
Volume	47
Issue	7

Summary

Year: 1994

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	GLUCAN SYNTHETASE INHIBITION(1-3)-BETA-D	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN A-0	ACTIVE
2	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-0	ACTIVE
3	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-0	ACTIVE
4	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-0	ACTIVE
5	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-0	ACTIVE
6	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-0	ACTIVE
7	HEMOLYTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN A-0	INACTIVE
8	GLUCAN SYNTHETASE INHIBITION(1-3)-BETA-D	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN A-2	ACTIVE
9	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-2	ACTIVE
10	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-2	ACTIVE
11	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-2	WEAK ACTIVITY
12	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-2	ACTIVE
13	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-2	INACTIVE
14	HEMOLYTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN A-2	ACTIVE
15	GLUCAN SYNTHETASE INHIBITION(1-3)-BETA-D	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN A-4	ACTIVE
16	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-4	ACTIVE
17	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-4	ACTIVE
18	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-4	ACTIVE
19	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-4	WEAK ACTIVITY
20	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN A-4	INACTIVE
21	HEMOLYTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN A-4	INACTIVE
22	GLUCAN SYNTHETASE INHIBITION(1-3)-BETA-D	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN B-0	STRONG ACTIVITY
23	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-0	ACTIVE
24	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-0	STRONG ACTIVITY
25	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-0	ACTIVE
26	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-0	ACTIVE
27	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-0	ACTIVE
28	HEMOLYTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN B-0	INACTIVE
29	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-2	INACTIVE
30	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-2	ACTIVE
31	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-2	WEAK ACTIVITY
32	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-2	ACTIVE
33	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN B-2	INACTIVE
34	HEMOLYTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN B-2	INACTIVE
35	GLUCAN SYNTHETASE INHIBITION(1-3)-BETA-D	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN C-1	ACTIVE
36	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN C-1	WEAK ACTIVITY
37	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN C-1	ACTIVE
38	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN C-1	EQUIVOCAL
39	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN C-1	ACTIVE
40	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN C-1	INACTIVE
41	HEMOLYTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN C-1	ACTIVE

Zalerion arboricola (HYPHOMYCETES)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	PNEUMOCANDIN D-0	None
2	GLUCAN SYNTHETASE INHIBITION(1-3)-BETA-D	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN D-0	ACTIVE
3	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN D-0	ACTIVE
4	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN D-0	ACTIVE
5	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN D-0	WEAK ACTIVITY
6	ANTIPROTOZOAN ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN D-0	STRONG ACTIVITY
7	ANTIYEAST ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VIVOANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)	PNEUMOCANDIN D-0	ACTIVE
8	HEMOLYTIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	PNEUMOCANDIN D-0	INACTIVE