Citation 76019

HORIGUCHI,T: HAYASHI,K: TSUBOTANI,S: IINUMA,S: HARADA,S: TANIDA,S:. (1994). NEW NAPHTHACENECARBOXAMIDE ANTIBIOTICS, TAN-1518 A AND B, HAVE INHIBITORY ACTIVITY AGAINST MAMMALIAN DNA TOPOISOMERASE I.. 47(5)

Citation Details

TitleNEW NAPHTHACENECARBOXAMIDE ANTIBIOTICS, TAN-1518 A AND B, HAVE INHIBITORY ACTIVITY AGAINST MAMMALIAN DNA TOPOISOMERASE I.
AuthorsHORIGUCHI,T: HAYASHI,K: TSUBOTANI,S: IINUMA,S: HARADA,S: TANIDA,S:
Year1994
Volume47
Issue5

Summary

Year: 1994

Journal: Unknown

Organisms and Their Experiments (1)

Streptomyces species (STREPTOMYCETACEAE)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
None
2
ANTITUMOR ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
3
ANTIMYCOBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
4
ANTIYEAST ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
5
ANTIFUNGAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
6
ANTIFUNGAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
7
ANTIYEAST ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
8
ANTIYEAST ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
9
ANTIYEAST ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
10
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
WEAK ACTIVITY
11
ANTIMYCOBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
12
ANTIMYCOBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
13
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
WEAK ACTIVITY
14
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
WEAK ACTIVITY
15
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
WEAK ACTIVITY
16
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
WEAK ACTIVITY
17
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
WEAK ACTIVITY
18
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
WEAK ACTIVITY
19
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
20
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
21
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
22
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
23
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
24
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
25
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
26
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
27
ANTIBACTERIAL ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
INACTIVE
28
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
29
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
30
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
31
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
32
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
33
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
34
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
35
TOPOISOMERASE I INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
36
TOPOISOMERASE II INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
STREPTOMYCES ANTIBIOTIC TAN-1518-A
WEAK ACTIVITY
37
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-A
ACTIVE
38Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
None
39
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
40
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
41
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
42
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
43
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
44
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
45
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
46
TOPOISOMERASE I INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
47
TOPOISOMERASE II INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
STREPTOMYCES ANTIBIOTIC TAN-1518-B
WEAK ACTIVITY
48
CYTOTOXIC ACTIVITY
PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE
STREPTOMYCES ANTIBIOTIC TAN-1518-B
ACTIVE
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