Citation 76857

SILVERMAN,KC: CASCALES,C: GENILLOUD,O: SIGMUND,JM: GARTNER,SE: KOCH,GE: GAGLIARDI,MM: HEMIBUCH,BK: NALLIN-OMSTEAD,M: SANCHEZ,M: DIEZ,MT: MARTIN,I: ET:. (1995). ACTINOPLANIC ACIDS A AND B AS NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE.. 43(4)

Citation Details

TitleACTINOPLANIC ACIDS A AND B AS NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE.
AuthorsSILVERMAN,KC: CASCALES,C: GENILLOUD,O: SIGMUND,JM: GARTNER,SE: KOCH,GE: GAGLIARDI,MM: HEMIBUCH,BK: NALLIN-OMSTEAD,M: SANCHEZ,M: DIEZ,MT: MARTIN,I: ET:
Year1995
Volume43
Issue4

Summary

Year: 1995

Journal: Unknown

Organisms and Their Experiments (2)

Streptomyces species (STREPTOMYCETACEAE)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
ISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
ACTINOPLANIC ACID B
None
2
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ACTINOPLANIC ACID B
ACTIVE
3
GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ACTINOPLANIC ACID B
WEAK ACTIVITY
4
SQUALENE SYNTHASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ACTINOPLANIC ACID B
INACTIVE

Streptomyces species (STREPTOMYCETACEAE)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
ISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
ACTINOPLANIC ACID A
None
2
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ACTINOPLANIC ACID A
ACTIVE
3
GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ACTINOPLANIC ACID A
WEAK ACTIVITY
4
SQUALENE SYNTHASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ACTINOPLANIC ACID A
INACTIVE
5Not specified
ISOLATION AND IDENTIFICATION OF
ACTINOPLANIC ACID B
None
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