Citation 77086

OMURA,S: INOKOSHI,J: UCHIDA,R: SHIOMI,K: MASUMA,R: KAWAKUBO,T: TANAKA,H: IWAI,Y: KOSEMURA,S: YAMAMURA,S:. (1996). ANDRASTINS A-C, NEW PROTEIN FARNESYLTRASFERASE INHIBITORS PRODUCED BY PENICILLIUM SP. FO-3929. I. PRODUCING STRAIN, FERMENTATION, ISOLATION, AND BIOLOGICAL ACTIVITIES.. 49(5)

Citation Details

TitleANDRASTINS A-C, NEW PROTEIN FARNESYLTRASFERASE INHIBITORS PRODUCED BY PENICILLIUM SP. FO-3929. I. PRODUCING STRAIN, FERMENTATION, ISOLATION, AND BIOLOGICAL ACTIVITIES.
AuthorsOMURA,S: INOKOSHI,J: UCHIDA,R: SHIOMI,K: MASUMA,R: KAWAKUBO,T: TANAKA,H: IWAI,Y: KOSEMURA,S: YAMAMURA,S:
Year1996
Volume49
Issue5

Summary

Year: 1996

Journal: Unknown

Organisms and Their Experiments (1)

Penicillium species (HYPHOMYCETES)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDX-RAY CHRYSTALLOGRAPHIC STUDIESINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
ANDRASTIN A
None
2
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ANDRASTIN A
ACTIVE
3Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDX-RAY CHRYSTALLOGRAPHIC STUDIESINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
ANDRASTIN B
None
4Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDX-RAY CHRYSTALLOGRAPHIC STUDIESINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
ANDRASTIN C
None
5
INOSITOL PHOSPHATASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ANDRASTIN B
WEAK ACTIVITY
6
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
ANDRASTIN C
ACTIVE
7
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
CITREOHYBRIDONE A
ACTIVE
8
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
CITREOHYBRIDONE B
ACTIVE
9
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
CITREOHYBRIDONE A,ISO:
WEAK ACTIVITY
10
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
CITREOHYBRIDONE B,ISO:
INACTIVE
11
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
CITREOHYBRIDONOL
INACTIVE
12
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
CITREOHYBRIDDIONE A
INACTIVE
13
FARNESYL-PROTEIN TRANSFERASE INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
CITREOHYBRIDDIONE B
WEAK ACTIVITY
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