Citation 81837

MATSUZAKI,K: TAHARA,H: INOKOSHI,J: TANAKA,H:. (1998). NEW BROMINATED AND HALOGEN-LESS DERIVATIVES AND STRUCTURE-ACTIVITY RELATIONSHIP OF AZAPHILONES INHIBITING GP120-CD4 BINDING.. 51(11)

Citation Details

Title	NEW BROMINATED AND HALOGEN-LESS DERIVATIVES AND STRUCTURE-ACTIVITY RELATIONSHIP OF AZAPHILONES INHIBITING GP120-CD4 BINDING.
Authors	MATSUZAKI,K: TAHARA,H: INOKOSHI,J: TANAKA,H:
Year	1998
Volume	51
Issue	11

Summary

Year: 1998

Journal: Unknown

Organisms and Their Experiments (2)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHROMOPHILONE I,ISO:	WEAK ACTIVITY
2	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHROMOPHILONE II,ISO:	ACTIVE
3	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	SCLEROTIORIN	INACTIVE
4	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	RUBROROTIORIN	INACTIVE
5	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ROTIORIN	INACTIVE
6	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	LUTEUSIN A	WEAK ACTIVITY
7	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHROMOPHILONE V,ISO:	WEAK ACTIVITY
8	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHROMOPHILONE III,ISO:	WEAK ACTIVITY
9	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHROMOPHILONE IV,ISO:	WEAK ACTIVITY
10	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHAETOVIRIDIN A	INACTIVE
11	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHAETOVIRIDIN B	WEAK ACTIVITY
12	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	LUNATOIC ACID	INACTIVE
13	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTED	CHROMOPHILONE I,ISO: TETRAHYDRO:	None
14	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHROMOPHILONE I,ISO: TETRAHYDRO:	INACTIVE

Penicillium multicolor (HYPHOMYCETES)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CHROMOPHILONE III,ISO: DECHLORO:	None
2	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHROMOPHILONE III,ISO: DECHLORO:	INACTIVE
3	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CHROMOPHILONE III,ISO: DECHLORO: 8-ACETYL:	None
4	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CHROMOPHILONE III,ISO: DECHLORO: 8-ACETYL:	INACTIVE
5	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	OCHREPHILONE	None
6	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	OCHREPHILONE	WEAK ACTIVITY
7	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	BENZALDEHYDE,2-4-DIHYDROXY-6-(5-7-DIMETHYL-2-OXO-TRANS-3-TRANS-5-NONADIENYL)-3-METHYL:	None
8	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	BENZALDEHYDE,2-4-DIHYDROXY-6-(5-7-DIMETHYL-2-OXO-TRANS-3-TRANS-5-NONADIENYL)-3-METHYL:	INACTIVE
9	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	ROTIORIN,ISO:	None
10	GP120 BINDING TO CD4+ CELLS INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ROTIORIN,ISO:	ACTIVE
11	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	OCHREPHILONE,5-BROMO:	None

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