Citation 81872

MC DONALD,LA: ELDREDGE,GS: BARROWS,LR: IRELAND,CM:. (1994). INHIBITION OF TOPOISOMERASE II CATALYTIC ACTIVITY BY PYRIDOACRIDINE ALKALOIDS FROM A CYSTODYTES SP. ASCIDIAN: A MECHANISM FOR THE APPARENT INTERCALATOR-INDUCED INHIBITION OF TOPOISOMERASE II.. 37(22)

Citation Details

Title	INHIBITION OF TOPOISOMERASE II CATALYTIC ACTIVITY BY PYRIDOACRIDINE ALKALOIDS FROM A CYSTODYTES SP. ASCIDIAN: A MECHANISM FOR THE APPARENT INTERCALATOR-INDUCED INHIBITION OF TOPOISOMERASE II.
Authors	MC DONALD,LA: ELDREDGE,GS: BARROWS,LR: IRELAND,CM:
Year	1994
Volume	37
Issue	22

Summary

Year: 1994

Journal: Unknown

Organisms and Their Experiments (1)

Cystodytes species (ASCIDIACEA)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	KUANONIAMINE B,DEHYDRO:	None
2	DNA INTERCALATING EFFECT	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	KUANONIAMINE B,DEHYDRO:	WEAK ACTIVITY
4	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	KUANONIAMINE B,DEHYDRO:	WEAK ACTIVITY
5	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	KUANONIAMINE B,DEHYDRO:	INACTIVE
6	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	SHERMILAMINE C	None
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	SHERMILAMINE C	WEAK ACTIVITY
8	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	SHERMILAMINE C	WEAK ACTIVITY
9	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	SHERMILAMINE C	INACTIVE
10	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CYSTODYTIN J	None
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	CYSTODYTIN J	ACTIVE
12	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	CYSTODYTIN J	ACTIVE
13	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	CYSTODYTIN J	WEAK ACTIVITY
14	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	CYSTODYTIN A	None
15	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	KUANONIAMINE D	None
16	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	KUANONIAMINE D	WEAK ACTIVITY
17	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	KUANONIAMINE D	WEAK ACTIVITY
18	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	KUANONIAMINE D	WEAK ACTIVITY
19	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	SHERMILAMINE B	None
20	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	SHERMILAMINE B	WEAK ACTIVITY
21	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	SHERMILAMINE B	WEAK ACTIVITY
22	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	SHERMILAMINE B	INACTIVE
23	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	EILATIN	None
24	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	EILATIN	ACTIVE
25	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	EILATIN	INACTIVE
26	Not specified	ISOLATION AND IDENTIFICATION OF	DIPLAMINE	None
27	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITROANTICANCER AND/OR CYTOTOXICITY MARKER CODE	DIPLAMINE	ACTIVE
28	TOPOISOMERASE II INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	DIPLAMINE	ACTIVE
29	DNA INTERCALATING EFFECT	PHARMACOLOGY OF COMPOUND - IN VITRO	DIPLAMINE	WEAK ACTIVITY

Citation 81872

Citation Details

Summary

Organisms and Their Experiments (1)

Cystodytes species (ASCIDIACEA)

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