Citation 85725

HOLLER,U: KONIG,GM: WRIGHT,AD:. (1999). A NEW TYROSINE KINASE INHIBITOR FROM A MARINE ISOLATE OF ULOCLADIUM BOTRYTIS AND NEW METABOLITES FROM THE MARINE FUNGI ASTEROMYCES CRUCIATUSAND VARICOSPORINA RAMULOSA.. 1999()

Citation Details

Title	A NEW TYROSINE KINASE INHIBITOR FROM A MARINE ISOLATE OF ULOCLADIUM BOTRYTIS AND NEW METABOLITES FROM THE MARINE FUNGI ASTEROMYCES CRUCIATUSAND VARICOSPORINA RAMULOSA.
Authors	HOLLER,U: KONIG,GM: WRIGHT,AD:
Year	1999
Volume	1999
Issue

Summary

Year: 1999

Journal: Unknown

Organisms and Their Experiments (4)

Ulocladium botrytis (HYPHOMYCETES)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	ULOCLADOL	None
2	TYROSINE KINASE INHIBITION	PHARMACOLOGY OF COMPOUND - IN VITRO	ULOCLADOL	ACTIVE
3	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ULOCLADOL	INACTIVE
4	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ULOCLADOL	INACTIVE
5	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ULOCLADOL	INACTIVE
6	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ULOCLADOL	INACTIVE
7	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ULOCLADOL	INACTIVE
8	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ULOCLADOL	INACTIVE
9	ANTIALGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ULOCLADOL	INACTIVE
10	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	XANTHONE,1-HYDROXY-6-METHYL-8-(HYDROXY-METHYL):	None
11	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	XANTHONE,1-HYDROXY-6-METHYL-8-(HYDROXY-METHYL):	INACTIVE
12	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	XANTHONE,1-HYDROXY-6-METHYL-8-(HYDROXY-METHYL):	INACTIVE
13	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	XANTHONE,1-HYDROXY-6-METHYL-8-(HYDROXY-METHYL):	ACTIVE
14	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	XANTHONE,1-HYDROXY-6-METHYL-8-(HYDROXY-METHYL):	ACTIVE
15	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	XANTHONE,1-HYDROXY-6-METHYL-8-(HYDROXY-METHYL):	INACTIVE
16	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	XANTHONE,1-HYDROXY-6-METHYL-8-(HYDROXY-METHYL):	INACTIVE
17	ANTIALGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	XANTHONE,1-HYDROXY-6-METHYL-8-(HYDROXY-METHYL):	INACTIVE

Asteromyces cruciatus (HYPHOMYCETES)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	FURAN-3-CARBALDEHYDE,4-5-DIHYDRO: 2-4-DIMETHYL: (+):	None
2	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	FURAN-2-ONE,DIHYDRO-DIMETHYL: 3(S)-5(R):	None

Asteromyces cruciatus (HYPHOMYCETES)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OF	MANNITOL,D:ARABITOL,D:TREHALOSE,D:	None
2	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ARABITOL,D:	INACTIVE
3	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ARABITOL,D:	INACTIVE
4	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ARABITOL,D:	ACTIVE
5	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ARABITOL,D:	ACTIVE
6	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ARABITOL,D:	INACTIVE
7	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ARABITOL,D:	INACTIVE
8	ANTIALGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ARABITOL,D:	INACTIVE

Varicosporina ramulosa (HYPHOMYCETES)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	COLLETODIOL,6(R)-11(R)-12(R)-14(R):	None
2	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,6(R)-11(R)-12(R)-14(R):	INACTIVE
3	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,6(R)-11(R)-12(R)-14(R):	INACTIVE
4	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,6(R)-11(R)-12(R)-14(R):	INACTIVE
5	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,6(R)-11(R)-12(R)-14(R):	INACTIVE
6	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,6(R)-11(R)-12(R)-14(R):	INACTIVE
7	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,6(R)-11(R)-12(R)-14(R):	INACTIVE
8	ANTIALGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,6(R)-11(R)-12(R)-14(R):	INACTIVE
9	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	ERGOSTEROL	None
10	Not specified	ISOLATION AND IDENTIFICATION OFPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDQUANTITATIVE DATA	COLLETOKETOL	None
11	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETOKETOL	INACTIVE
12	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETOKETOL	INACTIVE
13	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETOKETOL	INACTIVE
14	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETOKETOL	INACTIVE
15	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETOKETOL	INACTIVE
16	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETOKETOL	INACTIVE
17	ANTIALGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETOKETOL	INACTIVE
18	Not specified	ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA	COLLETODIOL,9-10-DIHYDRO: 6(R)-9-11(S)-12(S)-14(R):	None
19	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	None
20	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
21	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
22	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
23	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
24	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
25	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
26	ANTIALGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
27	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
28	ANTIBACTERIAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
29	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
30	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	ACTIVE
31	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
32	ANTIFUNGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE
33	ANTIALGAL ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	COLLETODIOL,9-10-DIHYDRO: 6(R)-11(R)-12(R)-14(R):	INACTIVE

Citation 85725

Citation Details

Summary

Organisms and Their Experiments (4)

Ulocladium botrytis (HYPHOMYCETES)

Asteromyces cruciatus (HYPHOMYCETES)

Asteromyces cruciatus (HYPHOMYCETES)

Varicosporina ramulosa (HYPHOMYCETES)

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