Citation 87991

HARDT,IH: STEINMETZ,H: GERTH,K: LASSE,F: REICHENBACH,H: HOFLE,G:. (2001). NEW NATURAL EPOTHILONES FROM SORANGIUM CELLULOSUM, STRAINS SO CE90/B2 AND SO CE90/D13: ISOLATION, STRUCTURE ELUCIDATION, AND SAR STUDIES.. 64(7)

Citation Details

Title	NEW NATURAL EPOTHILONES FROM SORANGIUM CELLULOSUM, STRAINS SO CE90/B2 AND SO CE90/D13: ISOLATION, STRUCTURE ELUCIDATION, AND SAR STUDIES.
Authors	HARDT,IH: STEINMETZ,H: GERTH,K: LASSE,F: REICHENBACH,H: HOFLE,G:
Year	2001
Volume	64
Issue	7

Summary

Year: 2001

Journal: Unknown

Organisms and Their Experiments (1)

Sorangium cellulosum (SORANGIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	UV SPECTRUM GIVEN FORISOLATION AND IDENTIFICATION OFMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATA	EPOTHILONE A	None
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE A	STRONG ACTIVITY
3	Not specified	UV SPECTRUM GIVEN FORISOLATION AND IDENTIFICATION OFMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATA	EPOTHILONE B	None
4	Not specified	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE B	STRONG ACTIVITY
5	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE E	None
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE E	STRONG ACTIVITY
7	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE F	None
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE F	STRONG ACTIVITY
9	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE A-1	None
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE A-1	STRONG ACTIVITY
11	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE A-2	None
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE A-2	STRONG ACTIVITY
13	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE A-8	None
14	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE A-8	STRONG ACTIVITY
15	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE A-9	None
16	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE A-9	ACTIVE
17	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE B-10	None
18	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE B-10	STRONG ACTIVITY
19	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE G-1	None
20	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE G-1	STRONG ACTIVITY
21	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE G-2	None
22	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE G-2	STRONG ACTIVITY
23	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE H-1	None
24	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE H-1	ACTIVE
25	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE H-2	None
26	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE H-2	STRONG ACTIVITY
27	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C	None
28	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C	STRONG ACTIVITY
29	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE D	None
30	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE D	STRONG ACTIVITY
31	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-1	None
32	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-1	ACTIVE
33	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE D-1	None
34	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE D-1	STRONG ACTIVITY
35	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-2	None
36	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-2	ACTIVE
37	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE D-2	None
38	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE D-2	STRONG ACTIVITY
39	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-3	None
40	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-3	ACTIVE
41	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-4	None
42	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-4	ACTIVE
43	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-5	None
44	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-5	ACTIVE
45	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE D-5	None
46	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE D-5	ACTIVE
47	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-6	None
48	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-6	ACTIVE
49	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-7	None
50	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-7	ACTIVE
51	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-8	None
52	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-8	ACTIVE
53	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-9	None
54	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-9	ACTIVE
55	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-1,TRANS:	None
56	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-1,TRANS:	ACTIVE
57	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE C-2,TRANS:	None
58	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE C-2,TRANS:	ACTIVE
59	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE I-1	None
60	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE I-1	ACTIVE
61	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE I-2	None
62	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE I-2	ACTIVE
63	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE I-3	None
64	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE I-3	ACTIVE
65	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE I-4	None
66	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE I-4	ACTIVE
67	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE I-5	None
68	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE I-5	ACTIVE
69	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE I-6	None
70	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE I-6	ACTIVE
71	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	EPOTHILONE K	None
72	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	EPOTHILONE K	ACTIVE
73	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	KETONE 37,DIHYDROXY:	None
74	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	KETONE 37,DIHYDROXY:	ACTIVE
75	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	KETONE 38,HYDROXY:	None
76	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	KETONE 38,HYDROXY:	INACTIVE
77	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	KETONE 39,HYDROXY:	None
78	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	KETONE 39,HYDROXY:	INACTIVE
79	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CARBOXYLIC ACID 40,DIHYDROXY:	None
80	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CARBOXYLIC ACID 41,DIHYDROXY:	None
81	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CARBOXYLIC ACID 42,METHOXY:	None

Citation 87991

Citation Details

Summary

Organisms and Their Experiments (1)

Sorangium cellulosum (SORANGIACEAE)

Show SPARQL Queries (1)

Query 1