Citation 88556

PRAKASH,CV: HOCH,JM: KINGSTON,DGI:. (2002). STRUCTURE AND STEREOCHEMISTRY OF NEW CYTOTOXIC CLERODANE DITERPENOIDS FROM THE BARK OF CASEARIA LUCIDA FROM THE MADAGASCAR RAINFOREST.. 65(2)

Citation Details

Title	STRUCTURE AND STEREOCHEMISTRY OF NEW CYTOTOXIC CLERODANE DITERPENOIDS FROM THE BARK OF CASEARIA LUCIDA FROM THE MADAGASCAR RAINFOREST.
Authors	PRAKASH,CV: HOCH,JM: KINGSTON,DGI:
Year	2002
Volume	65
Issue	2

Summary

Year: 2002

Journal: Unknown

Organisms and Their Experiments (1)

Casearia lucida (FLACOURTIACEAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN A	None
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN A	ACTIVE
13	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN B	None
14	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN C	None
15	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	ACTIVE
16	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	WEAK ACTIVITY
17	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	WEAK ACTIVITY
18	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	WEAK ACTIVITY
19	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	WEAK ACTIVITY
20	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	ACTIVE
21	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	ACTIVE
22	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	ACTIVE
23	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	ACTIVE
24	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN C	WEAK ACTIVITY
25	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN D	None
26	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	ACTIVE
27	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	WEAK ACTIVITY
28	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	ACTIVE
29	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	WEAK ACTIVITY
30	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	WEAK ACTIVITY
31	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	ACTIVE
32	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	ACTIVE
33	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	ACTIVE
34	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	ACTIVE
35	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN D	WEAK ACTIVITY
36	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN E	None
37	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
38	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
39	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
40	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
41	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
42	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
43	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
44	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
45	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
46	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CASEARLUCIN E	ACTIVE
47	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN F	None
48	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN G	None
49	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN H	None
50	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN I	None
51	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN J	None
52	Not specified	UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	CASEARLUCIN K	None
53	Not specified	ISOLATION AND IDENTIFICATION OF	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	None
54	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
55	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
56	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
57	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
58	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
59	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
60	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
61	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
62	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
63	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,DIACETOXY-18(S)-19(R)-EPOXY-6-HYDROXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
64	Not specified	ISOLATION AND IDENTIFICATION OF	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	None
65	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
66	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
67	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
68	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
69	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
70	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
71	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
72	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
73	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
74	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-6-METHOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-6R-8S-9S-10R): REL:	ACTIVE
75	Not specified	ISOLATION AND IDENTIFICATION OF	CLERODA-3-13(16)-14-TRIENE,18-19-DIACETOXY-18(S)-19(R)-EPOXY-2-(2-XI-METHYL-BUTANOYL-OXY): (2S-5R-8S-9S-10R): REL:	None

Citation 88556

Citation Details

Summary

Organisms and Their Experiments (1)

Casearia lucida (FLACOURTIACEAE)

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Query 1