Citation 88842

SCHUMACHER,B: SCHOLLE,S: HOLZL,J: KHUDEIR,N: HESS,S: MULLER,CE:. (2002). LIGNANS ISOLATED FROM VALERIAN: IDENTIFICATION AND CHARACTERIZATION OF A NEW OLIVIL DERIVATIVE WITH PARTIAL AGONISTIC ACTIVITY AT A-1 ADENOSINE RECEPTORS.. 65(10)

Citation Details

TitleLIGNANS ISOLATED FROM VALERIAN: IDENTIFICATION AND CHARACTERIZATION OF A NEW OLIVIL DERIVATIVE WITH PARTIAL AGONISTIC ACTIVITY AT A-1 ADENOSINE RECEPTORS.
AuthorsSCHUMACHER,B: SCHOLLE,S: HOLZL,J: KHUDEIR,N: HESS,S: MULLER,CE:
Year2002
Volume65
Issue10

Summary

Year: 2002

Journal: Unknown

Organisms and Their Experiments (1)

Valeriana officinalis (VALERIANACEAE)

Experiment #Pharmacology TypeWorktypesCompoundResults
1Not specified
VOUCHER SPECIMEN REPORTED FOR
NoneNone
2Not specified
ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA
MASSONIRESINOL-4'-O-BETA-D-GLUCOSIDE
None
3
SEROTONIN (5-HT) RECEPTOR BINDING DECREASED
PHARMACOLOGY OF COMPOUND - IN VITRO
MASSONIRESINOL-4'-O-BETA-D-GLUCOSIDEOLIVIL,9-O-(6''-DEOXY-SACCHAROSYL): 4'-O-BETA-D-GLUCOPYRANOSIDEBERCHEMOL-4'-O-BETA-D-GLUCOSIDEPINORESINOL-4-4'-DI-O-BETA-D-GLUCOSIDEPINORESINOL,8-HYDROXY: 4'-O-BETA-D-GLUCOSIDEPINORESINOL,8'-HYDROXY: 4'-O-BETA-D-GLUCOSIDEPINORESINOL,8'-HYDROXY:PINORESINOL-4-O-BETA-D-GLUCOSIDE
INACTIVE
4
RECEPTOR BINDING(BENZODIAZEPINE) DECREASED
PHARMACOLOGY OF COMPOUND - IN VITRO
MASSONIRESINOL-4'-O-BETA-D-GLUCOSIDEOLIVIL,9-O-(6''-DEOXY-SACCHAROSYL): 4'-O-BETA-D-GLUCOPYRANOSIDEBERCHEMOL-4'-O-BETA-D-GLUCOSIDEPINORESINOL-4-4'-DI-O-BETA-D-GLUCOSIDEPINORESINOL,8-HYDROXY: 4'-O-BETA-D-GLUCOSIDEPINORESINOL,8'-HYDROXY: 4'-O-BETA-D-GLUCOSIDEPINORESINOL,8'-HYDROXY:PINORESINOL-4-O-BETA-D-GLUCOSIDE
INACTIVE
5
GABA RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
MASSONIRESINOL-4'-O-BETA-D-GLUCOSIDEOLIVIL,9-O-(6''-DEOXY-SACCHAROSYL): 4'-O-BETA-D-GLUCOPYRANOSIDEBERCHEMOL-4'-O-BETA-D-GLUCOSIDEPINORESINOL-4-4'-DI-O-BETA-D-GLUCOSIDEPINORESINOL,8-HYDROXY: 4'-O-BETA-D-GLUCOSIDEPINORESINOL,8'-HYDROXY: 4'-O-BETA-D-GLUCOSIDEPINORESINOL,8'-HYDROXY:PINORESINOL-4-O-BETA-D-GLUCOSIDE
INACTIVE
6
ADENOSINE A-1 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
MASSONIRESINOL-4'-O-BETA-D-GLUCOSIDE
ACTIVE
7
ADENOSINE A2 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
MASSONIRESINOL-4'-O-BETA-D-GLUCOSIDE
INACTIVE
8Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
OLIVIL,9-O-(6''-DEOXY-SACCHAROSYL): 4'-O-BETA-D-GLUCOPYRANOSIDE
None
9
ADENOSINE A-1 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
OLIVIL,9-O-(6''-DEOXY-SACCHAROSYL): 4'-O-BETA-D-GLUCOPYRANOSIDE
ACTIVE
10
ADENOSINE A2 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
OLIVIL,9-O-(6''-DEOXY-SACCHAROSYL): 4'-O-BETA-D-GLUCOPYRANOSIDE
ACTIVE
11Not specified
UV SPECTRUM GIVEN FORMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDINFRARED SPECTRUM REPORTED FORQUANTITATIVE DATAISOLATION OF A COMPOUND WITH NOVEL STRUCTURE
BERCHEMOL-4'-O-BETA-D-GLUCOSIDE
None
12
ADENOSINE A-1 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
BERCHEMOL-4'-O-BETA-D-GLUCOSIDE
ACTIVE
13
ADENOSINE A2 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
BERCHEMOL-4'-O-BETA-D-GLUCOSIDE
WEAK ACTIVITY
14Not specified
ISOLATION AND IDENTIFICATION OFQUANTITATIVE DATA
PINORESINOL-4-4'-DI-O-BETA-D-GLUCOSIDE
None
15Not specified
ISOLATION AND IDENTIFICATION OF
PINORESINOL,8-HYDROXY: 4'-O-BETA-D-GLUCOSIDE
None
16
ADENOSINE A-1 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
PINORESINOL,8-HYDROXY: 4'-O-BETA-D-GLUCOSIDE
WEAK ACTIVITY
17
ADENOSINE A2 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
PINORESINOL,8-HYDROXY: 4'-O-BETA-D-GLUCOSIDE
WEAK ACTIVITY
18Not specified
ISOLATION AND IDENTIFICATION OF
PINORESINOL,8'-HYDROXY: 4'-O-BETA-D-GLUCOSIDE
None
19
ADENOSINE A-1 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
PINORESINOL,8'-HYDROXY: 4'-O-BETA-D-GLUCOSIDE
WEAK ACTIVITY
20
ADENOSINE A2 RECEPTOR BINDING INHIBITION
PHARMACOLOGY OF COMPOUND - IN VITRO
PINORESINOL,8'-HYDROXY: 4'-O-BETA-D-GLUCOSIDE
WEAK ACTIVITY
21Not specified
ISOLATION AND IDENTIFICATION OF
PINORESINOL,8'-HYDROXY:
None
22Not specified
ISOLATION AND IDENTIFICATION OF
PINORESINOL-4-O-BETA-D-GLUCOSIDE
None
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