Citation 89600

THALE,Z: JOHNSON,T: TENNEY,K: WENZEL,PJ: LOBKOVSKY,E: CLARDY,J: MEDIA,J: PIETRAZKIEWICZ,H: VALERIOTE,FA: CREWS,P:. (2002). STRUCTURES AND CYTOTOXIC PROPERTIES OF SPONGE-DERIVED BISANNULATED ACRIDINES.. 67(26)

Citation Details

Title	STRUCTURES AND CYTOTOXIC PROPERTIES OF SPONGE-DERIVED BISANNULATED ACRIDINES.
Authors	THALE,Z: JOHNSON,T: TENNEY,K: WENZEL,PJ: LOBKOVSKY,E: CLARDY,J: MEDIA,J: PIETRAZKIEWICZ,H: VALERIOTE,FA: CREWS,P:
Year	2002
Volume	67
Issue	26

Summary

Year: 2002

Journal: Unknown

Organisms and Their Experiments (3)

Unknown organism

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE	ACTIVE
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE	ACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE	ACTIVE

Xestospongia exigua (PETROSIIDAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
13	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
14	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
15	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
16	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
17	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
18	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
19	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
20	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
21	Not specified	ISOLATION AND IDENTIFICATION OFMASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTED	AMPHIMEDINE,NEO:	None
22	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
23	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
24	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
25	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
26	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
27	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
28	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	AMPHIMEDINE,NEO: 5-METHOXY:	None
29	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	ACTIVE
30	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	ACTIVE
31	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	ACTIVE
32	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	INACTIVE
33	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	INACTIVE
34	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	INACTIVE

Xestospongia carbonaria (PETROSIIDAE)

Experiment #	Pharmacology Type	Worktypes	Compound	Results
1	Not specified	VOUCHER SPECIMEN REPORTED FOR	None	None
2	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
3	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	INACTIVE
4	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	WEAK ACTIVITY
5	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	WEAK ACTIVITY
6	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
7	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	EQUIVOCAL
8	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	WEAK ACTIVITY
9	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	WEAK ACTIVITY
10	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
11	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
12	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF EXTRACT - IN VITRO	None	ACTIVE
13	Not specified	ISOLATION AND IDENTIFICATION OF	AMPHIMEDINE,NEO:	None
14	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
15	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
16	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
17	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
18	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
19	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO:	ACTIVE
20	Not specified	ISOLATION AND IDENTIFICATION OF	AMPHIMEDINE,NEO: 5-METHOXY:	None
21	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	ACTIVE
22	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	ACTIVE
23	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	ACTIVE
24	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	INACTIVE
25	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	INACTIVE
26	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	AMPHIMEDINE,NEO: 5-METHOXY:	INACTIVE
27	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	AMPHIMEDINE Y,NEO:	None
28	Not specified	MASS-SPECTRAL FRAGMENTATION REPORTEDPMR SPECTRUM REPORTEDCMR SPECTRUM REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	AMPHIMEDINE Z,NEO:	None
29	Not specified	ISOLATION OF A COMPOUND WITH NOVEL STRUCTURE	ALPKINIDINE	None
30	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ALPKINIDINE	WEAK ACTIVITY
31	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ALPKINIDINE	WEAK ACTIVITY
32	CYTOTOXIC ACTIVITY	PHARMACOLOGY OF COMPOUND - IN VITRO	ALPKINIDINE	WEAK ACTIVITY