Experiment 1017095

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)

Compounds isolated

COUMARIN,7-HYDROXY-4-METHYL:COUMARIN,7-ACETOXY:

Alerts

DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
ANTICERCARIAL ACTIVITY
Administration routeEXTERNAL
OrganismEmpty organism
CitationLOPES,JLC: LOPES,JNC: MELLO,RT: PELLEGRINO,J: VIEIRA,PC:. (1980). CHEMOPROPHYLACTIC STUDY ON SCHISTOSOMIASIS. IV. INHIBITION OF CERCARIAL PENETRATION BY COUMARIN DERIVATIVES.. 40()
Amount utilized
Compound isolated
DiseaseLESS THAN 70% PROTECTION.AFTER APPLICATION OF 100 CERCARIA TO THE TAIL AFTER IT HAD BEEN TREATED WITH THE TST COMPOUND.
Number1
Qualitative resultWEAK ACTIVITY
AnimalMOUSE
Dose expressionCONC USED