Experiment 1025414

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CYCLOHEX-2-EN-1-ONE,2-CROTONYL-OXY-METHYL-4-5-6-TRIHYDROXY:

Details

PropertyValue
Pharmacology
DNA POLYMERASE ALPHA INHIBITION
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationSUGIMOTO,Y: SUZUKI,H: YAMAKI,H: NISHIMURA,T: TANAKA,N:. (1982). MECHANISM OF ACTION OF 2-CROTONYLOXYMETHYL-4,5,6-TRIHYDROXYCYCLOHEX-2-ENONE, A SH INHIBITORY ANTITUMOR ANTIBIOTIC, AND ITS EFFECT ON DRUG-RESISTANT NEOPLASTIC CELLS.. 35()
Amount utilized
Compound isolated
Dose amount800.0 MCG
Number3
Qualitative resultACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionIC50