Experiment 1027085
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | WANG,CY: BUTA,JG: MOLINE,HE: HRUSCHKA,HW:. (1980). POTATO SPROUT INHIBITION BY CAMPTOTHECIN, A NATURALLY OCCURRING PLANT GROWTH REGULATOR.. 105() |
| Amount utilized | |
| Compound isolated | |
| Disease | TECHNICAL GRADE CAMPTOTHECIN CONTAINING 10-20% 10-METHOXYCAMPTOTHECIN WAS APPLIED TO THE EYES OR SPROUTS ON POTATOES AS LANOLIN SUSPENSIONS (1.5-15 MILLIMOLS) OR TO THE WHOLE TUBERS AS AQUEOUS SPRAYS OR DIPS AT VARIOUS CONCENTRATIONS. POTATO SPROUTING AT 15 C WAS COMPLETELY INHIBITED FOR 4 WEEKS BY ALL THE LANOLIN SUSPENSIONS.INHIBITION WAS GREATER THAN 95% WHEN 5 X 10(-1) MILLIMOLS WAS APPLIED TO THE TUBERS AS A 3-SPRAY OR 3-DIP TREATMENT. THE CAMPTOTHECIN TREATMENTS THAT INHIBITED SPROUTING ALSO REDUCED WEIGHT LOSS OF POTATO TUBERS: EVEN AFTER 4 MONTHS AT 15 C, NO SYMPTOMS OF INTERNAL SPROUTING OR OTHER DELITERIOUS EFFECTS WERE EVIDENT. ELECTRON MICROGRAPHS OF SPROUTS SUGGEST THAT CAMPTOTHECIN INHIBITED SPROUTING BY INDUCING STRUCTURAL CHANGES IN VASCULAR TISSUES AND INTERFERING WITH CELL DIVISION IN THE MERISTEMATIC PORTIONS OF THE SPROUTS. |
| Dose amount | 1.5 MILLIMOLS |
| Number | 1 |
| Qualitative result | ACTIVE |
| Dose expression | CONC USED |