Experiment 1049304

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOCARCINOGENIC DATA (MARKER CODE)TOXICITY MARKER CODE

Compounds isolated

SIMPLEXIN

Details

PropertyValue
Pharmacology
TUMOR PROMOTING EFFECT
Administration routeEXTERNAL
OrganismPimelea simplex (THYMELAEACEAE)
CitationHAFEZ,A: ADOLF,W: HECKER,E:. (1983). ACTIVE PRINCIPLES OF THE THYMELAEACEAE. III. SKIN IRRRITANT AND COCARCINOGENIC FACTORS FROM PIMELEA SIMPLEX.. 49(1)
Amount utilized
Compound isolated
DiseaseAPPLIED TO BACK SKIN TWICE WEEKLY,20 ANIMALS IN GROUP OF 28 DEVELOPED 84 TUMORS IN 24 WEEKS AFTER 100 NM DMBA INITIATION.
Dose amount20.0 NANOMOLS
Number3
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionDOSE