Experiment 1055797
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | GASTRIC INTUBATION |
| Organism | Empty organism |
| Citation | KAWADA,T: SUZUKI,T: TAKAHASHI,M: IWAI,K:. (1984). GASTROINTESTINAL ABSORPTION AND METABOLISM OF CAPSAICIN AND DIHYDROCAPSAICIN IN RATS.. 72(3) |
| Amount utilized | |
| Compound isolated | |
| Disease | 85% OF THE DOSE WAS ABSORBED INTO THE GASTROINTESTINAL TRACT WITHIN 3 HRS. WITHIN 60 MINUTES OF IN SITU ADMINISTRATION TO STOMACH, JEJUNUM AND ILEUM 50, 60, AND 70% OF THE DOSE WAS ABSORBED RESPECTIVELY. THE TRITIATED DRUG WAS ABSORBED MAINLY THROUGH THE PORTAL SYSTEM BUT NOT A MESENTERIC LYMPHANGIAL ONE. THE PORTAL BLOOD WAS COMPOSED OF 85% OF THE TRITIATED DRUG AND 15% OF ITS METABOLITE. HYDROLIZING ENZYME ACTIVITY WAS FOUND IN JEJUNAL TISSUE. |
| Dose amount | 3.0 MG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | ANIMAL |
| Dose expression | DOSE |